COVID-19 — Coronavirus

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More good news. Was just thinking - which country will be first to start roll out of a vaccine? There are now several that appear close to getting approval and you’d think the convenience surrounding the Oxford one would mean we may be fortunate enough to be first
 
More good news. Was just thinking - which country will be first to start roll out of a vaccine? There are now several that appear close to getting approval and you’d think the convenience surrounding the Oxford one would mean we may be fortunate enough to be first
Yeah a big plus this one is UK based.

Call me a cynic but no matter what we've paid to international companies there's little to stop them selling to another higher bidder or a Trump like grasp by some countries.
 
From what I read and hear, people who have worries over such a hurriedly developed and trialed vaccine, aren't anti vaxxers as such, but are concerned with any long term side effects, that whatever the government say to allay those fears, can only be proven with time itself...
But it’s not ‘time’ as such that’s going to prove it. It’s other people going first. So those that’s say ‘I’m going to wait and see’ are really saying ‘I’ll let someone else take the risk’. And if we all say that, then what?
 
Fantastic news from Oxford/Astrazeneca. Good enough is good enough - slightly lower efficacy than reported for Pfizer/Moderna doesn't matter.

Hopefully sufficient supplies to get our whole population vaccinated by the middle of next year, and to make a decent start on the entire world. This vaccine is cheap enough for any country (being provided at cost initially, 5-10x cheaper than Pfizer/Moderna)

Need our blues to improve quickly, 'cos we might just, if everything goes perfectly and with a following wind, see a full crowd for the FA cup final the way this is going now.

Rejoice! The end is in sight!

[and FFS keep up the social distancing. A lot of people could die yet in the next six months]
 
Hopefully the government will embark on a public awareness campaign to allay any fears and expose any myths being perpetrated by the anti-vaxxers.
It may need some shock tactics, a bit like the smoking ads. Show the distressing scenes of people in the last stage of life due to contracting Covid and then show how this can be avoided by a couple of routine vaccinations. The images of people dying on hospital floors in Northern Italy early this year were some of the most harrowing scenes I've ever seen, truly horrific.
 
It may need some shock tactics, a bit like the smoking ads. Show the distressing scenes of people in the last stage of life due to contracting Covid and then show how this can be avoided by a couple of routine vaccinations. The images of people dying on hospital floors in Northern Italy early this year were some of the most harrowing scenes I've ever seen, truly horrific.
Tell the morons they won't be able to go on holiday, go in pubs, even work. I will tell you now that every steward/stewardess won't be getting on a plane if they have had no vaccine.
 
It may need some shock tactics, a bit like the smoking ads. Show the distressing scenes of people in the last stage of life due to contracting Covid and then show how this can be avoided by a couple of routine vaccinations. The images of people dying on hospital floors in Northern Italy early this year were some of the most harrowing scenes I've ever seen, truly horrific.

I think it will be more effective if they just deploy David Attenborough to inform, plus a few others that are trusted.
 
Brilliant news.
Tbh it's been a bit quiet on the anti-vaxx front (at least the more conservative ones). Probably as sick to death of life at the moment as everyone else...and this is sounding like a fast track way out of this.
I've also seen a lot of 'debunking' articles on the web over the past week. Perhaps it's embarrassing them into submission.

Whilst this AZ/Oxford news is fantastic there's still a huge amount of optimism around the mRNA vaccines: not only for COVDI19 but for other potential diseases (and cancers) in the near future. Think it's surprised a lot of people and already a few are heralding it as important as the discovery of penicillin.
 
Great news this morning. Still confident we will be taking this vaccine.

Work will now begin to validate the manufacturing process, this work will take AT LEAST 2-4 weeks.
Unfortunately with setups like this, it's made in umpteen locations and each will have to be validated. Regulatory review will commence during this time and answers will be provided immediately. Pending no major findings, I'd expect approval/validation around Christmas time. Then the race is on to distribute.

Nice to see no corners cut. Vaccine is stable at 2-8C for up to 6 months and an anticipated 100s millions of doses should be available immediately after regulatory approval.
 
Great news this morning. Still confident we will be taking this vaccine.

Work will now begin to validate the manufacturing process, this work will take AT LEAST 2-4 weeks.
Unfortunately with setups like this, it's made in umpteen locations and each will have to be validated. Regulatory review will commence during this time and answers will be provided immediately. Pending no major findings, I'd expect approval/validation around Christmas time. Then the race is on to distribute.

Nice to see no corners cut. Vaccine is stable at 2-8C for up to 6 months and an anticipated 100s millions of doses should be available immediately after regulatory approval.
Can you recall how many doses of this vaccine the government ordered?
 
Hopefully the government will embark on a public awareness campaign to allay any fears and expose any myths being perpetrated by the anti-vaxxers.

I would expect they will but we all know that some people will never be persuaded and some of those will base their views on something completely irrational.


Anyone know if the vaccine contains animal products? I guess some will not have it if it has.
 
Brilliant news.
Tbh it's been a bit quiet on the anti-vaxx front (at least the more conservative ones). Probably as sick to death of life at the moment as everyone else...and this is sounding like a fast track way out of this.
I've also seen a lot of 'debunking' articles on the web over the past week. Perhaps it's embarrassing them into submission.

Whilst this AZ/Oxford news is fantastic there's still a huge amount of optimism around the mRNA vaccines: not only for COVDI19 but for other potential diseases (and cancers) in the near future. Think it's surprised a lot of people and already a few are heralding it as important as the discovery of penicillin.

Yes, this is the bigger thing for the mRNA things. A real major breakthrough, Nobel-winning stuff really.
 
There was an interesting article in the Guardian yesterday talking about the various developments on COVID vaccines and other treatments.

Both the pfizer and Moderna vaccines are both pretty similar and work in similar ways: they are injected into the muscle and from there they work their way into the bloodstream and stimulate the production of antibodies. But both have question marks though, for example how long such antibody resistance would last. Also the extent to which a heathy, but infected vaccinated person can still infect someone else.

Something which had not really occurred to me is that other types of treatment are also being researched, which potentially could be a whole lot better. Coronavirus gets in to your system through your mucous membrane, and therefore if we could kill it there, then for the virus it's game over. It never gets to make it further into your body.

There's research going on into such treatments which could take the form of a simple nasal spray or inhaler. And the advantages of these - as well as not having to arrange millions of injections - would be that people didn't carry the infection around and would not infect other people, so the disease would die out much more quickly.
 
Fantastic news from Oxford/Astrazeneca. Good enough is good enough - slightly lower efficacy than reported for Pfizer/Moderna doesn't matter.

Hopefully sufficient supplies to get our whole population vaccinated by the middle of next year, and to make a decent start on the entire world. This vaccine is cheap enough for any country (being provided at cost initially, 5-10x cheaper than Pfizer/Moderna)

Need our blues to improve quickly, 'cos we might just, if everything goes perfectly and with a following wind, see a full crowd for the FA cup final the way this is going now.

Rejoice! The end is in sight!

[and FFS keep up the social distancing. A lot of people could die yet in the next six months]
its very very good news. I class myself as quite a strong character, Im not easily upset and always try to make the best of things while suporting my family. Its also fair to say I have had more than my fair share of knocks in life especially that last year. However these past few months have been very difficult. Trying to keep a small business going and staff moral up has been hard work. Also to keep my families spirits up has been tough at times. I was in the City centre on Friday and it was really sad to see how quiet it was and it really brought things home to me again. The news has been constantly negative the last 9 mths which hasnt helped. Luckily I still have an income, my immediate family are still healthy and we have food on the table every night, and as a small business i am proud to say we have not had to lay any body off and i am convinced we will survive, so we are very fortunate. But I dont mind admitting that trying to remain optimistic has been really hard work. Goodness knows how others less fortunate have faired with livelihoods lost let alone their very close loved ones lost. That said I am convinced sunnier times lay ahead next year. Stay sensible and safe.
 
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There was an interesting article in the Guardian yesterday talking about the various developments on COVID vaccines and other treatments.

Both the pfizer and Moderna vaccines are both pretty similar and work in similar ways: they are injected into the muscle and from there they work their way into the bloodstream and stimulate the production of antibodies. But both have question marks though, for example how long such antibody resistance would last. Also the extent to which a heathy, but infected vaccinated person can still infect someone else.

Something which had not really occurred to me is that other types of treatment are also being researched, which potentially could be a whole lot better. Coronavirus gets in to your system through your mucous membrane, and therefore if we could kill it there, then for the virus it's game over. It never gets to make it further into your body.

There's research going on into such treatments which could take the form of a simple nasal spray or inhaler. And the advantages of these - as well as not having to arrange millions of injections - would be that people didn't carry the infection around and would not infect other people, so the disease would die out much more quickly.

Interesting. I hadn't heard of those options - I assume they are down the line as they are theoretical, but that solution has merit of it can be made to work.

The three made so far all work by capping the spike protein, with the idea of stopping the virus getting into the cell.
 
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