Us having no manufacturing base is a total myth. Our manufacturing value has never been higher but it is indeed thanks to automation, still a high tech skill base is required to grow it. A prime example is Leyland Trucks near me who year on year build more and more trucks yet they have probably 10,000 less staff than they did 20 years ago. I've been to their line and where 10 people once stood a robot does the same thing but at 10 times the speed. How can manufacturing justify not putting that robot there when it increases production by 10 times? Because it can do that it means the product cost can be reduced and therefore the company could compete on better terms. Without that edge, there may not even be a product to sell at all meaning no-one has a job.
If you base 'real' manufacturing on the old dirty manufacturing then yes that is dead because we have moved on from the 1970's. Steel and coal are no longer possible to produce viably in this country unless you want to get a group together to work for a pittance like the Chinese do who produce a lot of it now. The Chinese average yearly wage is around £6000 a year, is anyone willing to work full time for that nowadays? No, that equals a dead steel industry.
If you ask me, stop shopping in Primark, stop shopping in Poundland, Aldi and all the others and that is how you will revitalize the high street. These companies are directly responsible for driving down costs and therefore the big companies that once employed hundreds of thousands have now been replaced by companies that adapted to employ a third as many. When you reduce costs, the customer always wins and unfortunately that too comes at a cost to a workforce. Companies like Aldi may pay more and look like 'proper' companies but they run at a third or less the staffing levels of other retailers so can afford to. Had they suddenly had to pay twice as many people, you can bet their wages would come crashing down to reflect the others.
Shopping attitudes have changed and the market is now a race to the bottom where the only winner will be the one with the lowest costs which is usually the one with the least amount of people. People want cheap stuff and the only way to make it cheaper is to reduce how many people it takes to get it to the customer or to pay them the least amount possible.
It sounds awful but the best aspect of human nature must come into play in all of this unfortunately, you have to either adapt or die.