Its a tough call. I would love to see Kompany/Mangala work but I've seen no evidence whatsoever that they can work in tandem. I just think Vinny needs some no nonsense centre half to partner him which we haven't really got since Lescott left. MD and Mangala look uncomfortable with Vince so that leaves Denayer which is a huge risk. Our attacking intent doesn't help them and our problematic left-back position needs addressing as soon as possible. Pellers wont change his ways as regards to chopping and changing and utilising the whole squad but I've always believed in a stable back 4 and keeper or at least keeping the centre half pairing and keeper.
If I had to pick at this present moment. I would have a back line of Hart, Zabba, and Komps and take a risk in giving Denayer his chance, I would also pick Clichy over Kolarov just for his defensive duties. Tough games away I would play the back 4 as stated and use Delph and Fernandinho as protection and Toure in a more advanced role with Sterling playing slightly left with Silva having a free role trying to find the pockets of space and leave Sergio alone up top. De Bruyne coming in would give us another dimension altogether and we could forfeit Delph or Fernandinho for him and play Toure a little deeper. Should be interesting how much game time Bony, Nasri, Navas and Fernando get not to mention players not mentioned.