We have 2 really important, must win, probably must win and make a statement games coming up. For me, i would sacrifice the Cup game for them. Also considering that many of the regulars for the United and CSKA games have already played 3 games in 7 days. For me, I'd start with
-------------------------Willy---------------------------------
Sagna------Demi--Boyata/Nasty/Mangal---Clichy-
--------------Fernandinho----Fernando----------------
Navas--------------Pozo----------Jovetic/Nasri------
-----------------------Dzeko-------------------------------
My reasons:
1) All the back 4 Zabba, Komp, Mangala and Kolarov start for both the derby and CSKA so they should be given rest
2) Fernandinho wasnt used on Saturday and was a sub for the CSKA game. I would start him for both the derby and CSKA, but he can play for an hour and be substituted for Milner, who for me is also a starter for both CSKA and united games.
3) Silva, Yaya and Kun all need rest.
4) If we arent too convinced with boyata or Nasty partnering Demi, then I think its fine if Mangala gets more playing time. Playing alonside a cool head like Demi will help him
5) Jovetic starts only because I think he needs game time, for me he is a starter at the derby too. Although if Nasri can play I would give Nasri an hour and Jovetic 30 mins
This will then give us a fresh, balanced, and match sharp starting line up v the rags:
-------------------------Hart------------------------
Zabba------Komps----Mangala---Kolarov
--------------Yaya---------Fernandinho------
Milner--------------Silva-------------Jovetic
-----------------------Aguero---------------------
With Milner swapping sides if Di Maria is on the other flank, moving Jovetic central and Silva right. This lineup will also allow us to move to 433 quickly if united pack the midfield by going to a diamond formation
-------------------------Hart------------------------
Zabba------Komps----Mangala---Kolarov
------------Milner--Yaya--Fernandinho-----
Silva-----------------------------------------Jovetic
-----------------------Aguero---------------------