Coronavirus (2021) thread

[Healdplace]

And writing a book is quick?

For a year or two I had to write a book from start to finish in 6 weeks.

But that was because they were tied into a TV series and had to be written, edited and printed to be out in stores alongside the show which was only edited a few weeks before it aired.

So I guess it depends on the book she is writing,

On the other hand I started one in 2002 and am still working on that one! Not really a hurry as the publisher who commissioned it went out of business a few years ago.

 

[Healdplace]

UK scientists back Covid boosters as study finds post-jab falls in antibodies

Exclusive: Waning antibody levels are possible warning sign of lower protection in months after vaccination

www.theguardian.com

Backing up some of the Israel findings I suppose. Scientists argue that decline in antibodies is expected but the rate of decline has them slightly concerned. Boosters.

That is a pretty damning report on the AZ vaccine v Pfizer or am I reading it wrong?

Is it saying vastly lower antibodies levels in AZ only a few weeks on from second dose? As that sounds rather worrying if true. Given as more than 50% of the UK have had that.

I know antibodies are not everything. And T cells might be more important but is it the way the vaccines work that AZ loses so much anti body generation quickly and Pfizer a lot less so?

And does it matter as much as many reading that will be scared into imagining?

I guess if everyone who had AZ now gets Pfizer this autumn we will soon know.

 

[Didsbury Dave]

That is a pretty damning report on the AZ vaccine v Pfizer or am I reading it wrong?

Is it saying vastly lower antibodies levels in AZ only a few weeks on from second dose? As that sounds rather worrying if true. Given as more than 50% of the UK have had that.

I know antibodies are not everything. And T cells might be more important but is it the way the vaccines work that AZ loses so much anti body generation quickly and Pfizer a lot less so?

And does it matter as much as many reading that will be scared into imagining?

I guess if everyone who had AZ now gets Pfizer this autumn we will soon know.

I’m not surprised at all. I know it is totally unscientific but the fact that both my wife and I caught covid quite badly 2 months after being double jabbed rang big alarm bells with me. Same with a friend. I’ve suspected they are keeping research like this as quiet as they can for a while now.

 

[Rammy Blue]

I’m not surprised at all. I know it is totally unscientific but the fact that both my wife and I caught covid quite badly 2 months after being double jabbed rang big alarm bells with me. Same with a friend. I’ve suspected they are keeping research like this as quiet as they can for a while now.

We need a Pfizer booster in Sept.

 

[BlueAnorak]

I’m not surprised at all. I know it is totally unscientific but the fact that both my wife and I caught covid quite badly 2 months after being double jabbed rang big alarm bells with me. Same with a friend. I’ve suspected they are keeping research like this as quiet as they can for a while now.

Your just in the unlucky 30%. The question is how badly did you catch it?

 

[shemnel]

That is a pretty damning report on the AZ vaccine v Pfizer or am I reading it wrong?

Is it saying vastly lower antibodies levels in AZ only a few weeks on from second dose? As that sounds rather worrying if true. Given as more than 50% of the UK have had that.

I know antibodies are not everything. And T cells might be more important but is it the way the vaccines work that AZ loses so much anti body generation quickly and Pfizer a lot less so?

And does it matter as much as many reading that will be scared into imagining?

I guess if everyone who had AZ now gets Pfizer this autumn we will soon know.

i wouldnt quite go as far as 'damning'. I know little of the medical science behind B & T cells, but AZ vaccinated patients having vastly lower antibody levels than Pfizer folks doesn't seem to be of huge concern, or at least it is caveated by the fact that antibody levels are not the ideal metric for overall protection going forward.

there'll be data out there on how the vaccines are performing in the real world, with hospitalisation and deaths, that they are not releasing as to not cause panic/anger, you can guarantee that

 

[Tommy_Catons_Perm]

And writing a book is quick?

How long did it take you to write your last book?

 

[inbetween]

That is a pretty damning report on the AZ vaccine v Pfizer or am I reading it wrong?

Is it saying vastly lower antibodies levels in AZ only a few weeks on from second dose? As that sounds rather worrying if true. Given as more than 50% of the UK have had that.

I know antibodies are not everything. And T cells might be more important but is it the way the vaccines work that AZ loses so much anti body generation quickly and Pfizer a lot less so?

And does it matter as much as many reading that will be scared into imagining?

I guess if everyone who had AZ now gets Pfizer this autumn we will soon know.

Everyone will see an antibody reduction in some undetermined period, they don't last forever because there is no longer any infection. Antibodies are only measured in order to determine that the immune system is responding but there are many forms in which the immune system can respond. I think the only major worry for the AZ vaccine in comparison to the mRNA vaccines is whether the antibodies are forming to attack the adenovirus vector as opposed to the spike protein. This has implications for future boosters as we will become immune to the vector and so the vaccine will stop working.

We still have no idea on what part the remainder of the immune system plays in an infection, clearly if you consider the ratio of cases to deaths at the moment, it's having a huge effect. Many people are still getting ill but that's to be expected, the critical thing is far less are getting ill and an extremely small number go on to die.

Don't forget that most people who have died haven't died from COVID but rather they've died due to an extreme immune system response in combination with other health conditions. This extreme response is now less pronounced as the immune system deals with things better as it's already primed by a prior infection or vaccine.

The best statistic at the minute to remember is that the most vulnerable people are the ones who have seen the greatest antibody drop off (given they were fully vaccinated several months ago). Yet even still today, case positivity, deaths and hospitalisations are lowest in these groups which is fantastic news. The majority of deaths and serious cases in hospital are in people who aren't vaccinated or outside of these age groups.

The vaccines are having an incredible effect and that cannot be understated.

 

[Del_Bosque]

UK scientists back Covid boosters as study finds post-jab falls in antibodies

Exclusive: Waning antibody levels are possible warning sign of lower protection in months after vaccination

www.theguardian.com

Backing up some of the Israel findings I suppose. Scientists argue that decline in antibodies is expected but the rate of decline has them slightly concerned. Boosters.

That’s strange

the consensus i’d seen was that the increased gap for pfizer and AZ had made them more effective

and that AZ got better the further you got out from 2nd dose

that said the 570 people is back of fag packet stuff, always take them with a pinch of salt after that South Africa AZBeta study probably set them back 6 months and turned out to be BS

 

[Healdplace]

How long did it take you to write your last book?

The one I just had to write 10,000 new words for and revise the rest took me a long hard slog working to 3 am many nights after posting late in here.

But most of that was writing it via Pdf which I had never done before. I started off like Jessica Fletcher on a typewriter with my first one many moons ago but by 25 years ago was writing them on a laptop by the pool in Florida.

Science is amazing in how fast it can make life easier.

But the older you get the harder it is to adjust to the new.

My point is I know what writing a book involves and would never assume they are all done the same way or to the same speed. Some just have to be done fast. Others can take years.

I suspect the last part of Game of Thrones might appear - eventually. But it has taken a very long time from someone with all the money in the world to make it easy. Because - reasons.