COVID-19 — Coronavirus

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Len Rum said:
Sorry if late to the debate but are you talking here about the AZ vaccine?
How do they know these details about effectiveness if the trial was done on a one dose basis with another given three weeks later I.e they've not reproduced the one shot only with no follow up scenario.?
The reason I ask is that Pfizer appear to have made this point by implication in saying they have no data on the effectiveness of one shot of their vaccine after three weeks if not followed by a second jab?
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My understanding from what the MHRA said is that AstraZeneca/Oxford tried multiple interval options, and judged it from what they saw.
 
Len Rum said:
Sorry if late to the debate but are you talking here about the AZ vaccine?
How do they know these details about effectiveness if the trial was done on a one dose basis with another given three weeks later I.e they've not reproduced the one shot only with no follow up scenario.?
The reason I ask is that Pfizer appear to have made this point by implication in saying they have no data on the effectiveness of one shot of their vaccine after three weeks if not followed by a second jab?
Click to expand...
The AZ vaccine had different dose length trails, i think i heard some upto 6 mths apart.
 
It does seem as though as though there are some question marks around lengthening the second dose interval but in the present circumstances I don't think we have any option.
I read that if we can roll the vaccine out quickly just to the over 75s the death rate reduces dramatically.
 
Len Rum said:
It does seem as though as though there are some question marks around lengthening the second dose interval but in the present circumstances I don't think we have any option.
I read that if we can roll the vaccine out quickly just to the over 75s the death rate reduces dramatically.
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I think that's fair.
The data will be published, but it's quite complicated to set out apparently due to the way that the Oxford trials were conducted.
I assume they've also been continuing with further trials/checking up on triallists in order to monitor their initial conclusions.

As you say, get it started with what they have to work on, and change it when it becomes apparent that there's something better.
 
Brilliant news just as COVID19 looked like it was going for the knockout. Has us on the ropes but we’ve got a real chance to fight back if we can hold on a little longer.
Echo some of the statements here: jan/feb are usually dull months anyway. Grab some books, boxsets & movies...go walk & run if you can and Easter will look like a bloody second coming!
 
mosssideblue said:
Agreed, it's been a struggle for us all. For me, being able to leave the house, feel safe and see the kids is top of my normality requests. If I can do that, it means most people's normalities, pubs, football grounds gyms etc, should all be there to be enjoyed
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My year has been one of work-eat-sleep. My mum is terminally ill so we see her only under very careful circumstances. Though as she only has months she cares less and isnt as strict. I agree with her. She needs to ‘live’ whilst she can.

im lucky, im self emp but been busy. My 2 little ones (8 and 5) are still obviously at home and although its been shite for them with no activities, pals round etc we still all have each other. My oldest is 19 at uni, he fine.

so although im dead lucky i still desire the normal things in life. Itll come but please dong think going on the piss is all i care about. Its low in my priorities

our big thing is going away. After a tough year with mental health we started going away for the night/weekend every six weeks. With a cheeky weekend away never more than 6 weeks away it cured me and life changed for the better. We covered our map in the kitchen with pins over 3 years, so for that to come to a sudden halt hit me hard.

so when i say normality i mean just that. But health comes first of course.
So all i need is “hang on in there for 2-3 more months” ... then thats what i need. The unknown is a struggle

happy NY to you and yours. Stay safe. Keep being a miserable sod, the change wouldnt suit you ;)
 
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