Naturally, this could easily happen.
For every action there is a natural reaction. When the first bacteria grew, their numbers will have got unsustainable and other kinds of bacteria evolved that fed on the original bacteria. When plants grew, aphids evolved to feed on them, then predictors came to feed on them, and them, and them...
Up in Scotland, we can hunt and kill wild deer because the particular part of Scotland their habitat lies is small, and if their numbers grow too large they can either eat too much of their grasses and start to starve to death because of a lack of food or their numbers and small territory means that disease spreads and they die. To stop either of these things happening we have intervened and started keeping their numbers in check.
With humans, there isn’t another species keeping our numbers in check, and we aren’t doing it ourselves. Eventually, there will be a natural reaction from the planet where we can’t sustain the food needed to feed everyone and there could be mass starvation; or mass starvation due to plants stopping growing or becoming toxic due to climate change. Or the seas could lose their currents due to the increase in non-saline water melting into it, and the knock-on effects of that would be devastating.
Also a natural reaction to being too many of us and us living too close to wildlife that we shouldn’t be, could be that a
real pandemic could wipe billions of us out. Something with a long incubation period that is widely spread and kills after a few weeks could easily pop up some day soon! There have been over 60 potential pandemic events since the turn of the Century. Nearly all of them have not become pandemics, but this Coronavirus has. Thankfully, it’s not been a serious one. It’s had a long incubation period and is widely spread but it’s not particularly deadly. But one day, maybe in our lifetime, something
really bad could happen.
Look at what happens to viruses and pandemics themselves:
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There is always a sharp rise and a peak and a sharp decline. Then look at the correlation between those and human population growth. We’re still on the rise, but we are acting like a virus to the planet and eventually there will be a natural reaction to see humans peak and then decline.
The only thing that will stop it is if we stop acting like a virus.
Everywhere that humans have been on the planet, going back tens of thousands of years, we have wiped out or started to wipe out the megafauna of that area. Of the all the megafauna that have ever lived while humans have been around, humans have made 60% of them extinct and have put nearly all the rest on the endangered species list. If you look at the human population as a megafauna, there’s only one way we head when you look at the trend of all the others.