National teams face numerous obvious handicaps. They're limited to players who are eligible and have declared to play for their national side, they've far less opportunity to train and play together as a team, etc.
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City, Bayern, Real, PSG, Barca, etc. - any top-top club team - should typically be better off than the best national side.
Spain's 2010 side was phenomenal though - but you'd need to compare that side to Barca's squad at the same time featuring Messi.
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So, if the present City squad were somehow magically eligible and were playing for the WC - we'd be heavy favorites to win it all - but since it's win or go home starting in the round of 16, any off game against a lucky opponent could see us out.