Someone please correct me if I'm wrong, but this t-cell stuff seems really hopeful and that it could explain an awful lot that we didn't previously had answered. Honestly feel like it could be the answer to a tonne of questions.
Been reading up on it quite a lot on this today, and the general importance of them, and it's left me feeling quite hopeful. Excuse my basic explanation, but I just want to put it out there to see what others think. I didn't know this before today, but t-cells, which are very important in fighting off infections, are produced by the Thymus gland. The Thymus gland, and this is common medical knowledge apparently, starts to become gradually less useful from puberty onwards, and usually stops being effective around the age of 75 or so. So basically, the older you get, the less t-cells you produce, until basically you start to produce none. If you're dead young, you've got a really healthy Thymus gland producing a shit tonne of t-cells to fight off infections.
Now studies emerging today show a notable correlation between people suffering with severe cases of coronavirus and a notably low level of t-cells. There's some suggestion that for whatever reason the virus is pulling the rug from under the t-cells, thus reducing the body's natural capability to fight off the infection. Obviously you've got less t-cells as you get older, but the research seems to suggest that people have less than they should in some cases. That BBC report a few posts back has given us news that they're going to trial a drug that could help people produce t-cells in the hope of fighting off this virus. Really encouraging, and hopefully it helps.
Could it be that t-cells are a lot more important than we realise and we've only got a small part of the overall immunity picture? It seems plausible that most people's mild cases, or asymptomatic ones could be explained by t-cells fighting it off instead, efficiently, thus reducing the need for a stronger antibody response. We could have spent an awful lot of time and energy looking for signs of antibodies to see how many have had it, but accidentally not given enough consideration to another part of the picture. T-cells. There are even some suggestions that our bodies' t-cells may have fought off other milder, common coronaviruses recently, thus giving some partial immunity to help fight off the virus, given they do share similarities.
There's seemingly a growing weight of evidence to suggest that this virus *could* be a lot more spread than we realise (many advise caution though obviously) and we've in fact been looking for proof that of the spread via quite a narrow measure - i.e just antibodies. It could be that we should be looking for signs of activated t-cells as well. The t-cells thing seems to explain why the virus seems to get worse as you get older, and also explains why children deal with this so well...
Now I may have summarised that incorrectly, but it seems very hopeful to me, and pretty logical too! Obviously though I don't want to explain it incorrectly or get anyone's hopes up, and sorry if I have. I'm just some random bloke who hasn't got a clue, so naturally I advise caution. Heh.