Think Mourinho will go into this reckoning he knows exactly what Pep will do so the best thing wecan do may be to switch it up a bit. Pack the midfield to overwhelm their Pogba-Herrera partnership. When Silva and De Bruyne get their short, sharp passing going the inexperienced Baily and the out-of-position Blind won't know how to deal with it and if Nolito comes in as a false 9 that will confuse them even more. Shaw and Valencia aren't the quickest and so I would say we start Sané and Sterling (Sterling and Navas if Sané isn't ready) to beat them down, keep them pinned back too as both offer an attacking threat. Fernandinho, with help from Kolarov and Sagna, should be able to deal with Mata and Rooney but I feel like we will need Sterling down the right hand side to combat Martial's pace as he is amongst their biggest threats in this game. Ibrahimovic should be dealt with nicely by the strength of Kompany and Kolarov and Stones can come forward to a CDM role when we're attacking, to help out Fernandinho.
Or, we could play a 4-4-2 :3
Or, we could play a 4-4-2 :3