COVID-19 — Coronavirus

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Does anyone know if this thing rapidly mutates?
There is conflicting evidence from what I have read and I have not seen any conclusive consensus that it is or is not (relatively) rapidly mutating.

I included that information as reference, as not having conclusive understanding of rate of mutation is also a big risk with this strategy.
 
Does anyone know if this thing rapidly mutates?
Yes. It's an RNA single stranded polynucleotide.

There is actually hope that it will evolve from a pathogenic virus to something that's none-lethal but that's not going to happen quickly enough
 
There is conflicting evidence from what I have read and I have not heard any conclusive statement that it is or is not (relatively) rapidly mutating.

I included that information as reference, as not having conclusive understanding of rate of mutation is also a big risk with this strategy.
It already has mutated slightly. The strain in Italy is different to that seen in China.

In fact there were two strains in China
 
but I see nations in the Pacific rim who have virtually defeated the virus.
.

I think they are a very long way from that. Some might have brought it under control to some degree but as soon as they relax those measures, there's a very high chance it will flare up again.
 
Herd immunity without vaccination takes time (usually years), is usually only effective against pathogens that do not rapidly mutate, usually only possible in relatively isolated populations without carrier exchange with other infected populations, requires a very large portion of the population to develop sufficient antibodies, and virtually ensures maximum potential severe outcomes and deaths over the course of development if there are no additional measures for population isolation and infection mitigation.

So using it as a sole real method of containment (even paired with optimised personal hygiene and social distancing) is the near equivalent of just letting the viral outbreak run its course and hoping for the best (i.e. that collectively the population will generate antibodies to the novel coronavirus sufficient to allow for the slowing of transmission until comprehensive vaccinations can begin).

Just want to clarify for those trying to determine if the strategy of attempting to build herd immunity in 6-9 months is the optimum path.

You say you're clarifying but you're being incredibly disingenuous because you're operating on the false assumption that there are no additional measures taken.
 
The stats from Spain, Germany, France and Italy all tell a similar story. A roughly 18% daily rise in cases and a similar percentage for deaths (apart from Germany). Our percentages are also similar so it looks like we’re a week behind Spain, France and Germany and two weeks behind Italy.. All are still exponential and it will be interesting to see when Italy’s starts to drop off as I suspect we’ll follow suit two weeks later.
 
It already has mutated slightly. The strain in Italy is different to that seen in China.

In fact there were two strains in China
Yes, the L- and S-types.

But that is what I was referring to with conflicting evidence, as there is also some evidence that is relatively stable (lower relative mutation rate).

I don’t want to give the impression there is overwhelming evidence it is mutating rapidly, just point out that not having a strong understanding of that is another issue with this strategy.
 
Why don't they roll out untested vaccines if they work in human trials? There are cases where a vaccine has actually made the infection worse because it produces a violent immune response. However wouldn't that show in the live trials.

It is not acceptable to not even try to stop this.
 
Why don't they roll out untested vaccines if they work in human trials? There are cases where a vaccine has actually made the infection worse because it produces a violent immune response. However wouldn't that show in the live trials.

It is not acceptable to not even try to stop this.
Marvin you are better than that question
 
You say you're clarifying but you're being incredibly disingenuous because you're operating on the false assumption that there are no additional measures taken.
I am not operating on any such false assumption and qualified as such in the post you quoted, specifically for that reason.

I was speaking to many posts that seemingly reference the building of herd immunity as a singular strategy for containment and/or slowing of transmission.
 
I am not operating on any such false assumption and qualified as such in the post you quoted, specifically for that reason.

I was speaking to many posts that seemingly reference the building of herd immunity as a singular strategy for containment and/or slowing of transmission.

No one has referenced building herd immunity as a singular strategy for containment, so the posts you claim to be replying to don't exist.
 
No one has referenced building herd immunity as a singular strategy for containment, so the posts you claim to be replying to don't exist.
They have referenced it in the context of delaying other necessary simultaneous actions such as enforced population isolation and transmission mitigation, which the government outlined yesterday. People don’t have to use the exact words to reference it, you of all people understand that.

It’s very odd that you read my post, with the qualifications, and thought I was operating on that false assumption.
 
Yes, the L- and S-types.

But that is what I was referring to with conflicting evidence, as there is also some evidence that is relatively stable (lower relative mutation rate).

I don’t want to give the impression there is overwhelming evidence it is mutating rapidly, just point out that not having a strong understanding of that is another issue with this strategy.
By the way that anti-viral I mentioned is already being used by the South Koreans in the treatment of their at risk coronavirus patients.
 
Sir Patrick said some of the social distancing measures put in place, including self-isolating for seven days if symptoms develop, were "actually quite extreme"

Christ,no wonder they thought mass crowds were fine
 
If you really require an answer to what seems to me a fairly inane question, then I’ll say Ireland. They seem to be more proactive in their response imo.
It was a genuine question. Personally I feel my family are safer and best protected here.
And I very much wish, you and yours the same.
 
Your first sentence.
Ok, I am actually confident in my understanding Of the timescale usually required for the building of herd immunity from past days of medical training and from speaking with medical professionals in my family — can you quote the bit in the article you linked that contradicts that it takes time to build herd humanity without vaccination (*usually* years)?
 
Surely he must feel whatever he is doing is for the best. Does anyone really know what the best thing to do is? Is there evidence that shutdown is working in other countries, or is it too early to tell?

I'm no big fan of Boris, just trying to understand.

He'+s a ****, but I doubt he is trying to kill as many Britons as he could. But doing it the way the UK is trying to do is seeking for glory, imo. Either him or the scientists he is listening to (or vice versa). The whole world is doing it one way and then you have few of them running UK that are going completely opposite. I just don't understand it.
 
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