On a more positive note, my wifes best friends dad has been let out of hospital today, after being in an induced coma for 10 days. He's apparently on the mend and now coronavirus free, when it was very touch and go for a while.
COVID-19 — Coronavirus
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kaz7
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We do get the difference in number from the day before for the critical care and Hosp admissions,i can't always catch those in amongst the other figures,i would like more of the figures that scotland give though
I can see the usual tables with the breakdowns on?
Think they’ve added a couple more too, male/female split still as shown before and survival rates similar too.
BlueAnorak
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The raw data table at the end isn't there.
BlueAnorak
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Impressive considering Athens is one of the most densly populated places in Europe. They did lock down early though.
I guess a lot depends on how many went skiing in the Italian Alps.
Fame Monster
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What's classed as an underlying health condition these days? I've just watched the news and there was a guy on there with COVID with 'no underlying health conditions'. He was about 30 stone?
Is anyone in the labs looking into Ouzo as a possible treatment?
Wow...first time in a few weeks this thread hasn't sat top of the table. The positive news thread may one day soon sit above this soon (and hey...dig the football analogy huh?)
Nebuchadnezzar
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I can only speak for myself in saying that this thread has oversaturated my brain. We have gone from glimmers of hope to hearing that this can give young people strokes as a side effect. This has possibly been the maddest thread I have ever seen on Bluemoon.
I’ve stayed off it for some time for that reason.
btw - I’ve just stuck Netflix on and there’s already a CV19 doc up - anyone seen it? Might be linked to the other virus doc (with bill gates)z
BlueAnorak
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Another scientific paper proves that Coronavirus is airborne in non-ventilated areas for many hours.
https://www.telegraph.co.uk/news/20...inger-air-crowded-spaces-toilets-hours-study/
https://www.telegraph.co.uk/news/20...inger-air-crowded-spaces-toilets-hours-study/
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kaz7
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Are you wearing a mask ?
kaz7
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Think that a bit much marvin,one of two paragraphs onlyNews I have copied from nature.com https://www-nature-com.manchester.idm.oclc.org/articles/d41586-020-00502-w
I have copied below because I am not sure if you need asubscription to access
Fresh findings about SARS-CoV-2 and the disease it causes.
27 April — Hospital toilets can be a hotspot for airborne viral RNA
The new coronavirus’s RNA can travel through the air, and might spread by way of small particles exhaled by infected people.
Ke Lan at Wuhan University in China and his colleagues tested the concentration of SARS-CoV-2 RNA in aerosols — fine airborne particles — at two hospitals treating people with COVID-19 (Y. Liu et al. Nature https://doi-org.manchester.idm.oclc.org/10.1038/s41586-020-2271-3; 2020).
The team detected elevated levels of viral RNA in locations such as a small toilet used by patients, and staff changing rooms. No viral RNA was detected in staff rooms after they had been disinfected. Low to undetectable levels were found in the hospitals’ well-ventilated patient wards.
The presence of airborne viral RNA suggests that SARS-CoV-2 has the potential to spread by way of aerosols, the researchers say. They suggest that measures such as routine disinfection and better ventilation could help to control the virus’s spread.
24 April — Spit could be the solution to testing shortages
A person’s saliva accurately reveals whether they are infected with SARS-CoV-2, a finding that could make tests for the virus safer and more widely available.
The gold-standard test for coronavirus infection requires a long swab to be rubbed against the back of the throat. But such swabs are in short supply, and swabbing can prompt people to cough or sneeze, potentially launching a barrage of viral particles.
Anne Wyllie at the Yale School of Public Health in New Haven, Connecticut, and her colleagues collected both saliva and throat samples from people hospitalized with COVID-19 (A. Wyllie et al. Preprint at medRxiv, http://doi.org.manchester.idm.oclc.org/ggssqf, 2020). The team’s testing did not detect the virus in some patients’ throat-swab samples — but did detect it in the same patients’ saliva samples. Saliva testing also showed that two health-care workers who felt fine and had negative throat tests were actually infected.
A human cell (blue; artificially coloured) infected with SARS-CoV-2 (yellow).Credit: NIAID/NATIONAL INSTITUTES OF HEALTH/SPL
23 April — Intensive testing finds a small town’s many silent infections
A large proportion of people with COVID-19 have no symptoms, according to research in a small Italian town.
On 21 February, the town of Vo’ reported Italy’s first COVID-19 death, leading authorities to ban movement in the town and end public services and commercial activities there for two weeks. Andrea Crisanti at Imperial College London and his colleagues swabbed almost every resident of Vo’ for viral RNA at the beginning and end of the lockdown.
The team found that some 43% of the people infected with SARS-CoV-2 in the town reported no fever or other symptoms (E. Lavezzo et al. Preprint at medRxiv http://doi.org.manchester.idm.oclc.org/ggsmcj; 2020). The researchers observed no statistically significant difference in potential infectiousness between those who reported symptoms and those who did not.
Asymptomatic and pre-symptomatic individuals have a key role in COVID-19 transmission, which makes it difficult to control the disease without strict social distancing, the authors say.
22 April — A vaccine candidate shows early success in an animal trial
An experimental vaccine protects monkeys from infection with the virus that causes COVID-19.
A team led by Chuan Qin at the Peking Union Medical College in Beijing injected rhesus macaques (Macaca mulatta) with three doses of a vaccine comprised of chemically inactivated particles of SARS-CoV-2 (Q. Gao et al. Preprint at bioRxiv http://doi.org.manchester.idm.oclc.org/dskt; 2020). Eight monkeys were then intentionally exposed to the virus.
All four monkeys given a high dose of the vaccine had no detectable virus in their throat or lungs seven days after exposure. Monkeys that received a lower dose of vaccine showed some signs of coronavirus infection — but their levels of virus were much lower than in exposed animals that received no vaccine. This month, the company developing the vaccine received approval to start human safety trials on it.
A man with COVID-19 is treated at an intensive care unit in Rome.Credit: Antonio Masiello/Getty
20 April — How Hong Kong stemmed viral spread without harsh restrictions
Hong Kong slowed the spread of SARS-CoV-2 through a combination of intensive surveillance, quarantining and social distancing without relying on severe measures used elsewhere.
In January, the authorities in Wuhan, where the coronavirus outbreak began, halted travel out of the city in an attempt to control the spread of the virus that causes COVID-19. But Hong Kong relied on a programme that included widespread testing, quarantining of those who had been in contact with infected people, and distancing measures such as school closures. When Peng Wu at the University of Hong Kong and her colleagues surveyed residents in early March, 99% said they wore a mask in public and 85% said they avoided crowds (B. J. Cowling et al. Lancet Public Health http://doi.org.manchester.idm.oclc.org/dsfw; 2020).
The combination of public behavioural changes and government measures kept the virus’s spread relatively low in Hong Kong during the period to the end of March, the team found.
17 April — Vaccine from viral spikes holds promise
A key portion of a coronavirus protein could form the basis of a safe and effective vaccine.
Coronavirus particles bristle with spiny ‘spike proteins’. A portion of the spike called the receptor-binding domain recognizes and attaches to a molecule found on the surface of many human cells, allowing the viral particle to gain entry into those cells.
Hyeryun Choe and Michael Farzan at the Scripps Research Institute in Jupiter, Florida, and their colleagues immunized rats with fragments of the spike’s binding domain (B. D. Quinlan et al. Preprint at bioRxiv, http://doi.org.manchester.idm.oclc.org/ggrs5t; 2020). In response, the rodents’ immune systems made antibodies that can recognize coronavirus and prevent it from infecting cells.
BlueAnorak
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My real name is Bruce Wayne.
kaz7
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"We do not enter the field of battle lightly... neither in heart, nor body, nor mind. Nor do we exit it lightly. We leave a piece of us behind. And sometimes the cost of defending the innocent exceeds what we could ever think to pay. There's only one word for this. Sacrifice. And whether it be recognized in the present... or in some distant time, or never at all... this is the hero's duty
That sounds like our nhs
kaz7
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I get told all the time it is a copyright not content thing,i was trying to help you and RIc ! It is an interesting read though
Fantastic structural diagram of SARS-CoV-2 and the receptor from a paper (Shang, J., Ye, G., Shi, K. et al. Structural basis of receptor recognition by SARS-CoV-2. Nature (2020)).
This is my interpretation of the diagram but it's not my subject so I maybe misleading you.
I think it's produced by X-ray diffraction. The contours represent electron density around atoms largely of carbon, nitrogen and hydrogen.
I think the green chain is a an helical structure formed by a long chain of amino acids that forms a polypeptide. I think this is part of the ACE 2 receptor from a respiratory cell. I am guessing that the the bottom structure is the human cell because proteins in cell membranes tend to have a helical structure whereas polypeptides elsewhere in the body take on a Beta sheet, and that's definitely a helical structure.
The virus particle bonds to the receptor cell through it's configuration and the interaction of charges on polarised atoms within the amino acids.
Don't you think that the shape which the molecule takes up time and time again is remarkable? When you look at biomolecules on this scale you realise that there is no elixir of life, it's just complex chemistry.
This science started about 100 years ago when the Bragg's father and son decoded the pattern of dots which a salt crystal makes when a beam of x-rays is fired at it. This is the science that was used to derive the structure of DNA, and gradually it's been used to look at more and more complicated molecules. Somehow someone has made a crystal structure out of the virus, and then fired x-rays at it to produce a diffraction pattern that has then been interpreted by a computer following some algorithm into a molecular structure.
There's a particle accelerator in Oxfordshire called the Diamond light which is used to generate the x-ray sources for experiments such as these.
kaz7
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American microbiologists from Harvard and Stanford on American tv saying antibody tests are not reliable for individual testing and giving accurate results,and immunity advice ,they are not getting accurate data for that use,wide scale using for getting a pic/survey can even out the results so they can get a picture across the population
Does herd immunity start at 50% ? More like 60%
Will there be a lower death rate than flu? Depends on each state,those with a younger age group and those who have really good healthcare that won't collapse v those with older age group in ill health and lot of care homes,impossible to say at the moment
Dictated off CNN news just now
Chief of neuro at Jefferson health
Strokes in young and middle aged patients with asymptomatic covid , 40% of patients under 50 and 50% of the patients had no risk factors for stroke
Anyone with covid symptoms,tested positive if not ,having any stroke symptoms must go to hospital
Pattern of clots were,different,both sides, multiple vessels. stroke was their first symptom of covid for some
Mortality in strokes normally 10% but in covid patients 50% despite retrieving the clots
Causing more damage to the body than expected,lung damage,kidney damage,there is a lot we don't know yet
Dictated off CNN
Does herd immunity start at 50% ? More like 60%
Will there be a lower death rate than flu? Depends on each state,those with a younger age group and those who have really good healthcare that won't collapse v those with older age group in ill health and lot of care homes,impossible to say at the moment
Dictated off CNN news just now
Chief of neuro at Jefferson health
Strokes in young and middle aged patients with asymptomatic covid , 40% of patients under 50 and 50% of the patients had no risk factors for stroke
Anyone with covid symptoms,tested positive if not ,having any stroke symptoms must go to hospital
Pattern of clots were,different,both sides, multiple vessels. stroke was their first symptom of covid for some
Mortality in strokes normally 10% but in covid patients 50% despite retrieving the clots
Causing more damage to the body than expected,lung damage,kidney damage,there is a lot we don't know yet
Dictated off CNN
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birchwoodgingerste
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Wow is there some sort of knowledge battle going on with kaz and marv?:))
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