COVID-19 — Coronavirus

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somapop said:
For those that know far more about vaccines than I, is there real cause for concern with the mink coronavirus jump?
From what I picked up on here, the CV19 was RNA based (which normally makes it more likely to mutate anyway) unlike DNA. However, so far, it doesn't look like it's mutating a great deal (unless this mink story urinates over that....)
Click to expand...
Can't say I know that much . But the problem with the mink variant as far as I understand it is that it is a variant of the spike protein which has been previously fairly well preserved and the spike protein is basically what is produced by the Oxford vaccine and several others , if there are significantly different antigenic properties between the old spike protein and the new it could affect the protection afforded by vaccination but this is not yet known.
 
Wales data first up today- and sadly still bad. Hope they know what they are doing by ending restrictions on Monday.

32 deaths tragically and 958 cases from 11.25K tests.
 
Wales 3 wks ago v 2 wks v last wk v today

Deaths 5 v 16 v 13 v 32 today

Cases 674 v 1324 v 1301 v 958 today.

Which is at least some sign of a downturn in cases.
 
A man who hosted a party of 60 in a two bedroom flat in Withy Grove last weekend fined £10,000 for his troubles.
 
Scotland data sadly pretty bad today

39 deaths

1591 cases at 6.3% positive

1245 in hospital (up 8)

106 icu ventilators up 8 - biggest daily rise in a while.
 
somapop said:
For those that know far more about vaccines than I, is there real cause for concern with the mink coronavirus jump?
From what I picked up on here, the CV19 was RNA based (which normally makes it more likely to mutate anyway) unlike DNA. However, so far, it doesn't look like it's mutating a great deal (unless this mink story urinates over that....)
Click to expand...

Don't know about this specific mutation, but corona viruses mutate slower than most RNA based viruses, so less likely to be an issue than with FLU, HIV etc

Viruses that encode their genome in RNA, such as SARS-CoV-2, HIV and influenza, tend to pick up mutations quickly as they are copied inside their hosts, because enzymes that copy RNA are prone to making errors...

...But sequencing data suggest that coronaviruses change more slowly than most other RNA viruses

www.nature.com

The coronavirus is mutating — does it matter?

Different SARS-CoV-2 strains haven’t yet had a major impact on the course of the pandemic, but they might in future.
www.nature.com www.nature.com
 
Scotland 3 wks ago v 2 wks v last wk v today

Deaths 15 v 11 v 24 v 39 today

Cases 1167 v 1433 v 1101 v 1591 - first time in a while a serious rise week to week

Patients 672 v 985 v 1149 v 1245 today

icu ventilators 62 v 85 v 80 v 106 today - after a fall in these there seems a concerning rise again here too.

Todays numbers are a bit of a worry so far.
 
England hospital deaths sadly are just as bad as the trend above.

283 - with 84 from the North West.

Also 82 from Yorkshire and 69 Midlands.

The only good news is that the NW split is still falling and it is the rise in other areas now mostly driving this increase from 208 last Saturday when there were 83 from the NW (just 1 less than today) and 36 each from the Midlands and Yorkshire (both well up on that number this week) proving this point.
 
roubaixtuesday said:
Don't know about this specific mutation, but corona viruses mutate slower than most RNA based viruses, so less likely to be an issue than with FLU, HIV etc

Viruses that encode their genome in RNA, such as SARS-CoV-2, HIV and influenza, tend to pick up mutations quickly as they are copied inside their hosts, because enzymes that copy RNA are prone to making errors...

...But sequencing data suggest that coronaviruses change more slowly than most other RNA viruses

www.nature.com

The coronavirus is mutating — does it matter?

Different SARS-CoV-2 strains haven’t yet had a major impact on the course of the pandemic, but they might in future.
www.nature.com www.nature.com
Click to expand...
Thanks for this.
Helps a bit.
Like many were just trying to find positives without falling over the edge into conspiracies which offers false warmth & comfort.
Add potent mutations into the mix and it can stir up more negativity.

Thanks for all the other replies too
 
Unfortunately Northern Ireland completes the awful data today.

15 deaths (most yet in second wave)

528 cases - which is the positive out of this as deaths would be the last number to change and the cases really are showing a good downward trek,

Indeed the rolling 7 day case number is down again as it is now every day - it is at 4007. And was over 7000 when the circuit breaker was introduced.

Patients 391 - which is 16 fewer than yesterday.

No data on ventilators but icu beds with covid up 4 to 53
 
Northern Ireland 3 wks ago v 2 wks v last wk v today

Deaths 2 v 6 v 11 v 15 today This will be the last to turn so let us hope it starts to fall soon.

Cases 1031 v 923 v 649 v 528 today - the steady fall week to week is happening daily so this is real and will hopefully translate into falling deaths soon.

7 day case total fell from 5285 a week ago to 4007 today.

Patients 231 v 309 v 346 v 391 today

Ventilators 22 v 27 v 41 v ??? (but max 4 increase of any based on icu bed increase)
 
somapop said:
Thanks for this.
Helps a bit.
Like many were just trying to find positives without falling over the edge into conspiracies which offers false warmth & comfort.
Add potent mutations into the mix and it can stir up more negativity.

Thanks for all the other replies too
Click to expand...

WHO assessment of the mink mutation

www.who.int

SARS-CoV-2 mink-associated variant strain – Denmark

Since June 2020, 214 human cases of COVID-19 have been identified in Denmark with SARS-CoV-2 variants associated with farmed minks, including 12 cases with a unique variant, reported on 5 November.
www.who.int www.who.int

Short version: Too early to judge significance. Keep studying, be cautious.
 
So total deaths from UK today is a tragic 369.

Last Saturday it was 256 and the all settings later became 326

We look likely to have a very sad number tonight once England out of hospital data added.
 
Cases today total are 3077 for the three nations


Over past month that is:

2872 3 wks ago v 3680 2 wks ago v 3051 last wk v 3077 today - which is the first rise in this number (all be it tiny) over the recent past of steady falls.
 
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