Coronavirus (2021) thread

[kaz7]

financial support? Not done bad at all on that either.

Ok i forgot that , rushi has done well

 

[worsleyweb]

Few words on the longevity of antibodies; this is the study current best knowledge is based on in the UK. That those with antibodies or a previous positive PCR have much lower reinfection rate than not.

The study concludes that after 5 months of follow up on this cohort, "prior SARS-CoV-2 infection protects most individuals against reinfection for at least five months".

Further follow up will provide more data but it is extremely likely, given the prevalence of antibodies after 5 months, that they'll last longer than that. Best knowledge = min 5 months for the vast majority

Do antibody positive healthcare workers have lower SARS-CoV-2 infection rates than antibody negative healthcare workers? Large multi-centre prospective cohort study (the SIREN study), England: June to November 2020

Background There is an urgent need to better understand whether individuals who have recovered from COVID-19 are protected from future SARS-CoV-2 infection. Methods A large multi-centre prospective cohort was recruited from publicly funded hospital staff in the UK. Participants attended regular...

www.medrxiv.org

bloody hell karen won’t like that! Come on Karen it could be longer than 5 months!

 

[Gabriel]

It’s all a bit.

‘8%, that’s what he said...’

 

[blue b4 the moon]

A direct text from someone very much in the know on our vaccine supply vs the eu.

Just seen on Euronews...they're not happy over there.

 

[Gaylord du Bois]

It’s all a bit.
View attachment 8978
‘8%, that’s what he said...’

It's Ronnie Kray.

 

[kaz7]

bloody hell karen won’t like that! Come on Karen it could be longer than 5 months!

I want it to last longer than five months , why wouldnt i ?

Preprint and not peer reviewed so care is needed

Whilst the exact length of immunity conferred by natural infection is still unknown, titres of neutralising antibodies against SARS-CoV-2 spike protein were detectable for at least five months after primary infection.30

 

[worsleyweb]

I want it to last longer than five months , why wouldnt i ?

Preprint and not peer reviewed so care is needed

Whilst the exact length of immunity conferred by natural infection is still unknown, titres of neutralising antibodies against SARS-CoV-2 spike protein were detectable for at least five months after primary infection.30

Only pulling your leg - good quote but add at the end “and extremely likely to last longer”

 

[cleavers]

about the only thing they have got right mind you

On vaccine's it's been good (so far), and they also got (and continue to get) the furlough scheme right, millions still have a job if/when normality comes back, at huge cost to the government.

They have also caused this current mess, by reacting far too late to the rapidly growing case numbers in early/mid December, the main reason that so many are currently dying.

It's very definitely at best a "mixed bag".

 

[roubaixtuesday]

I’d also add according to Scottish figures so far 45% of over 80s have been done and 96% of total vaccinations so far were with the pfizer which surprised me this afternoon. Don’t know for England.
Is it possible Pfizer is being used on the older and most vulnerable first, maybe most over 70s?

I think almost the opposite - there have been stories about the AZ vaccine being rolled out to places like care homes where the logistics of the Pfizer jab make it much harder. But I've not seen any figures.

 

[canyerdogputoutafire]

A vaccination centre opened last Monday twenty-five yards from my house. It is a seven day operation 8am-8pm. It operated last Mon, Wed and Friday and wasn't open today. I assume supply issues.

 

[ctwrd]

With the bans on foreign travel, our beaches are going to be busier this year than last year. Looking forward to bbc news interviewing sunbathers expressing their “surprise” that so many people are there once again. Yawn.

 

[SB Blue]

I’d also add according to Scottish figures so far 45% of over 80s have been done and 96% of total vaccinations so far were with the pfizer which surprised me this afternoon. Don’t know for England.
Is it possible Pfizer is being used on the older and most vulnerable first, maybe most over 70s?

My mum is 73 and had the Oxford jab in Eccles today, she didn’t have to wait for the 15 minutes observation although said some people had to so presumably they had Pfizer. Could be basing it on age in some locations?

 

[kaz7]

Only pulling your leg - good quote but add at the end “and extremely likely to last longer”

I have a quick read and it doesnt say it is extremely likely to last longer , trials report findings and not surmising past that

At least five months is what whitty says, after that him and this paper on trials cant say, we cant assume as we are all different , hence i act like i can get again

Going to bed but will read it again tomorrow

 

[squirtyflower]

And yet again, we have done nothing that EU membership precluded us from.

As confirmed by the head of the MHRA.

How come none of the other 27 countries took the chance then?

 

[Healdplace]

GM Scoreboard:

1003 - down 71 from 1074. 34.2% of North West Total which fell 408 to 2929. Rise of 2.0% on yesterday, Biggest day to day rise in a while.

3 wks v 2 wks v last wk v Today:- 1742 v 1571 v 1359 v 1003.

That is a very pleasing steady fall wk to wk over the new year.


Pop Score is cases across whole pandemic v 100,000 people - rises daily but lower the better.

Weekly Pop is same measure across last 7 days only. Can rise or fall depending on if more cases or less occur today v the same day last week.


Either way Up is bad, down is good.



Manchester 210 – down from 260. Total 44, 191. Weekly 1963. Below 2000 for first time in some time. Pop score up 38 to 7993. One of lowest rises in a while here, Weekly Pop down 17 to 355.

Bolton 117- up from 88. Total cases 20, 910. Weekly 961. Pop score up 41 to 7272. Weekly Pop down 9 to 334. Big week to week fall as despite rise in daily cases still lower than last week.

Wigan 108 - down from 135. Total cases 24, 160. Weekly 1076. Pop score up 33 to 7351. Weekly Pop down 24 to 327.

Stockport 100 – down from 110. Total cases 16, 717. Weekly 862. Pop score up 34 to 5697. Weekly Pop down 8 to 294. Another borough goes sub 300 to join Oldham at last.

Tameside 90 – up from 78. Total cases 14, 729. Weekly 746. Pop score up 40 to 6503. Weekly Pop down 6 to 329.

Salford 82 - down from 106. Total cases 19, 029. Weekly 858. Pop score up 32 to 7352. Weekly Pop down 17 to 332.

Oldham 78 - up from 76. Total cases 19, 471. Weekly 608. Pop score up 33 to 8212. Weekly Pop down 7 to 257.

Trafford 76- down from 84. Total cases 13, 867. Weekly 733. Pop score up 32 to 5842. Stockport's Pop Score lead cut by another 2 to 145. Weekly Pop down 2 to 308.

Rochdale 75 - down from 90. Total cases 17, 674. Weekly 690. Pop score up 34 to 7947.Weekly Pop down 19 to 311.

Bury 67- up from 47. Total cases 14, 377. Weekly 586. Holds onto lowest weekly total. Pop score up 35 to 7528. Weekly Pop goes down by 3 to 307.


Plenty of falls again and Stockport now second best borough with Pop score again after being sky high ay second worst close to going over 500 just 10 days ago and dropping 188 in that time.

 

[M18CTID]

Just a follow up to this story...

Sounds like the Der Spiegel hatchet job on City. Shithouses won’t fess up who their source is. Oxford/AZ should take it to CAS

 

[Invisible Man's Bandage]

I will speculate.

The UK information for healthcare professionals quotes:

The number of COVID-19 cases (2) in 660 participants ≥65 years old were too few to draw conclusions on efficacy

and

However, in this subpopulation, immunogenicity data are available, see below.

Summary of Product Characteristics for Vaxzevria - Last updated November 2023

www.gov.uk

In other words, the trial proved efficacy in the overall population, but the approval depends on showing equivalent immune response (antibody generation) in older subjects rather than efficacy directly.

My guess is that the very small numbers in the older age group means there is a very large confidence interval on efficacy in that age group, and the lower limit of the confidence interval is 8%. If so, it absolutely does not mean efficacy is 8%, and the MHRA view is that the demonstration of equivalent immune response is sufficient to justify temporary authorisation.

As I said, just speculation.

It surely wouldn't make sense to approve it at all if efficacy is only 8%? The Sanofi/GSK vaccine has had to start the whole trial process again as it was shown to be effective for younger age groups but far less for older groups. You can't imagine that one was only 8% either.

 

[kaz7]

With the bans on foreign travel, our beaches are going to be busier this year than last year. Looking forward to bbc news interviewing sunbathers expressing their “surprise” that so many people are there once again. Yawn.

God you are relentless

 

[cleavers]

My mum is 73 and had the Oxford jab in Eccles today, she didn’t have to wait for the 15 minutes observation although said some people had to so presumably they had Pfizer. Could be basing it on age in some locations?

Mines 79 and she had the Oxford (only 1 so far), my dad 82 had Pfizer, and he's had both doses.

 

[ayrshire_blue]

Sounds like the Der Spiegel hatchet job on City. Shithouses won’t fess up who their source is. Oxford/AZ should take it to CAS

Hopefully Prestwich Blue and projectriver are on the case.