I would stay on International Drive, anywhere between the Hilton Garden Inn, 5877 American Way and the Hyatt Regency, 9801 International Dr. It’s a 1 hour walk between these two and there’s 50 bars, restaurants & entertainment places. There’s also a trolley bus to jump on/off instead of walking. It is tourist central, some a little tacky, but everything is there. I would guess City will be at the Hyatt Regency.
Prices for hotels are creeping up every day. The Hampton Inn near Universal Blvd & Hampton Inn & Suites International Dr N, are both OK (think Premier Inn) and are +/- 130 quid per night. That’s probably the sweet spot for pricing, as less than 100 quid will be like a ropey Travelodge :O
The down town area is further North. 15 mins in an Uber. It’s OK, but a lot less to see & do compared to the International Drive area, called I-Drive by the locals.
Hope that helps.