Pep is a huge loss for you, as he would be for any club.
If it is Maresca, he has enormous footsteps to follow in.
I much prefer you to the other 'top six' clubs, but this squad is clearly weaker than in Pep's prime days when Silva x 2, De Bruyne, Sterling, Yaya, Kompany, Fernandinho, Rodri, Aguero were all in their prime or at least still very good.
But there's no real squad of that calibre anywhere in the Premier League, either. I see this as a transitional phase for City but still more than good enough to win the league with astute signings. I did think Semenyo was a player who doesn't really fit into how City usually play, but maybe you're going more direct now as with Haaland and will keep doing that. I am not really a big fan of Reijnders or Gonzalez but there are other players in your squad I like a lot (O'Reilly, Doku is starting to fulfil potential, Khusanov is improving all the time, and a few others).
Donnarumma I am not sure about - he's an excellent shot stopper usually but clearly nowhere near as comfortable with the ball at his feet as Ederson. I suppose it depends on what you want these days - I mean he can be serviceable at it, but it's more diffcult to play out from the back with him.
A lot also depends on summer acquisitions. Big summer coming up. But I think the safest bet is it being between Arsenal and City again. Rags are running on a hot streak and Liverpool and Chelsea have too many problems. Chelsea for one are run by venture capitalists with zero interest in winning, and last summer has messed Liverpool up, and if it Iraola, I am not convinced the squad can play to his style (though he may alter his style).
Clubs like the three Bs are very good and can beat anyone at any time, but not consistent enough to rack up enough points over the season to challenge.
A lot also depends on how much of this rugby style football continues to be permitted in the future.
Just some of my thoughts, feel free to disagree.
Overall, I think your centurion and treble teams would dominate this side (I don't think that is a controversial take), but this is a fairly young side with you'd imagine some more to come and some more reinforcements. Recruitment is key.