I cant name names for legal reasons but i have made one really bad career move.
I ended up working in a privately run public health laboratory as a principle scientist. My manager asked me to falsify results. I refused and reported him to his manager, who said he would investigate. A couple of days later i was auditing a piece of analytical equipment and found the lab had been releasing results we couldnt verify, which is against the law as these related to materials that subsequently entered the food chain. I didnt feel confident about reporting it to my boss as he had already asked me to falsify results, so i reported it to his boss, the man who was supposed to be investigating my boss. His response was astonishing, and I quote "dont worry its not the only place we are breaking the law". I spent about 2 hours mulling this over and then handed my notice in and reported them to the relevant authorities.
If I had been single my mulling would have been about 30 seconds, but as I was the sole wage earner with a wife and 2 kids a little longer was required.
Obviously taking the job was the bad career move. Quitting was a good career move