COVID-19 — Coronavirus

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Marvin said:
Most mutations are point mutations which are very small and still encode for the exact same amino acid, and so have no effect at all.

Prof Gilbert said that their MERS vaccine worked well on a whole variety of MERS strains.
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I don't think that's entirely accurate on the science, although the essence is correct.

It is true that most mutations are point mutations. It is very uncommon for a mutation to not change the amino acid, although it is probably possible on odd occasions.
What it may do is mutate in an inactive part of the virus, which is when it will have minimal impact.
 
Has there been any explanation of the hike in US numbers today?

It's really good to see the numbers of Spain, Italy and France continue to improve.
 
i8rags said:
You don’t think science has improved since the thalidomide scandal. Beyond belief
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Which is not what I posted. I commented that the science to prevent the scandal was available then but the testing was not thorough enough, in other words human inadequacy was the problem not the science. Even with improved science now if the testing isn't good enough...well you work it out.
 
Manc in London said:
Not sure who you are talking about. I got the info from a NYT article.

Easy to understand for someone like me who knows very little about viruses:

https://www.nytimes.com/interactive/2020/04/16/opinion/coronavirus-mutations-vaccine-covid.html
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The guy running the testing of the vaccine at Oxford university,he did an interview earlier,i posted it word for word and he was asked about the chinese saying 33 mutations and he said it shouldn't make a difference as there will be more than one vaccine tested anyway
 
karen7 said:
The guy running the testing of the vaccine at Oxford university,he did an interview earlier,i posted it word for word and he was asked about the chinese saying 33 mutations and he said it shouldn't make a difference as there will be more than one vaccine tested anyway
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Ah right. I thought the person running the Oxford tests was a female. That probably explains why I wasn't sure who you were referring too.

Have a read of the article. It's clear, concise and measured.
 
karen7 said:
The guy running the testing of the vaccine at Oxford university,he did an interview earlier,i posted it word for word and he was asked about the chinese saying 33 mutations and he said it shouldn't make a difference as there will be more than one vaccine tested anyway
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Think you mean Andrew Pollard

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Don't shoot the messenger stumbled on this on twitter, interesting stuff which will probably get shut down soon.

 
Looking at the latest Dr Campbell video.

WHO and Dutch scientists are saying that even in the worst hit areas right now infections will be no higher than 2-3% of the countries population.

going by that. And adjusting our deaths figures based on the ONS statement of death figures actually being about 41% higher than the official hospital figures.

the uk’s Estimated case fatality rate is about 1.3-1.9%.

all napkin maths here mind you.
 
There a dr on CNN tonite,he said they are finding with the antibody test that you can have a high level of antibodies but not have much immunity because it s not the number you have but how well they work,you need antibodies that work very well in blocking the virus,i suppose this is why it is difficult to get a great test and scientists hovering a bit on the immunity question
 
paulchapo said:
Don't shoot the messenger stumbled on this on twitter, interesting stuff which will probably get shut down soon.

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So those other countries agreed to trash their own economies so they could trash the USA's economy?

Seems a bit far-fetched, I reckon it was Rui Pinto looking for something else to pin on City.
 
Apparently, countries with obligatory vaccination against tuberculosis have some 10 times less infection and death rates than those where that vaccination is not obligatory.
 
Gelsons Dad said:
I'm afraid neither nurse Campbell or the WHO have any fucking idea.

Imperial College estimates:
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Thanks for posting that. I'd expected similarly low levels but useful to see another source suggesting same.

If anyone is still clinging to the herd immunity daft idea then that should kill it off.

Just 4% of the UK population infected has resulted in 20,000 dead already. Surely no-one can now think that allowing the rest of us to catch this can possibly be a good idea.

These figures bring with them some hope of a favourable long term outcome IMO.

1. They mean the overall death rate for infections is perhaps around 0.7% - and certainly under 1% - which although terrible compared to flu, is still much lower than the current headline figures.

2. It would seem to indicate it's not as infectious as other models might have suggested, or else more would be infected already.

3. If only 1 person in 25 you might bump into has had this - and a much lower number have currently got it and are infectious - then your chances of avoiding it by appropriate protections and social distancing might be relatively high. Were the community spread much more pervasive, then this would obviously be much less likely and chances are we'd all get it before a vaccine arrives. Now there is some hope that most of us can avoid it until a vaccine arrives.
 
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