COVID-19 — Coronavirus

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that wasn't how it was expressed on tonight's 6 o'clock news. They said what percentage had been given the placebo and of the remainder (who got the trial vaccine) only 5% of that amount contacted covid, therefore claiming 95% effective.

Im just curious as their logic didn't seem quite right to me
I'm curious about the 95% who did fall ill with the virus. Was everybody in the test group exposed at the same level of risk? If (I stress if) you were looking to make a great profit out of your vaccine, you could remove all (or 95%) of the vaccinated people out of any potential contact. Not at all claiming that is the case, but there is obviously a financial incentive, as well as the kudos, to be first.
 
My wife has just come home
she has worked on ITU at Tameside all through this fucking shit
she's just told me me of yet another death
a bloke in his late 60's
2 relatives only allowed to go in has they switched his life support machine off

talk all about your number etc

I'v had to listen to all these personal stories since March now

Iv been on an early myself and been drinking,sorry for letting off steam
It's fair play chap we all need to once in a while.

I'm constantly pulling myself back from boiling over.
 
I'm curious about the 95% who did fall ill with the virus. Was everybody in the test group exposed at the same level of risk? If (I stress if) you were looking to make a great profit out of your vaccine, you could remove all (or 95%) of the vaccinated people out of any potential contact. Not at all claiming that is the case, but there is obviously a financial incentive, as well as the kudos, to be first.
That is why the trials are conducted 'blindly ' so neither the people giving or getting the vaccine or placebo can tell.
 
Probably because they have been quoting deaths based on the date that they were reported throughout the pandemic. There are different ways of counting the deaths and you dismiss one of the methods. Fair enough.

The number of cases has also gone off daily reported positive tests as you also know. (The day before’s reported figures in both cases). We know from other surveys that those figures probably represent between a quarter and a half of the daily infections but that’s the main way the Government reports them.

The date of infection / death might be more accurate in both cases but the approach has been fairly consistent. The figures are sad whichever way you look at them.
I’m not suggesting otherwise but the truth has always been the way to approach this and it’s sadly lacking. Distorting it be using ‘date reported’ is just nonsensical and it’s what led to headlines of ’over 1000 deaths a day‘ in April, when the 1000 mark has never been breached. It’s sensationalist and just feeds people’s fears, although that might be what they’re trying to do, I suppose.
 
So how can they claim an effectiveness % without these challenge trials?

The way I understood the first one that they talked about was the when 180 of the 20k people who had the placebo have tested positive, that is enough for the results to be taken seriously. Obviously if 180 also caught it from the 20k that had the vaccine then it would be useless, but if only 10 do then we know it's 90% successful.
 
You divide say 10,000 people into two groups and give 5,000 the vaccine and 5,000 the placebo by random sorting.
After say 105 people have tested positive you unblind the trial to see how many were in each group. If there were 100 in the placebo group and 5 in the vaccine group, you then make the following assumption that 100 people were exposed to the virus enough to develop symptoms and be tested positive. Because the groups are randomly allocated you assume that the exposure for each group is similar. If only 5 people in the vaccine group; are positive this implies that the vaccine is 95% effective. This is clearly an estimate and the statisticians then have to calculate the confidence intervals around the number to satisfy the regulator that the estimate is good enough.
Thanks, that makes more sense
 
Just to say more. Might be a while as I work through the numbers today as they are utterly ludicrous based on the published data. The student farce has created utter utter chaos.

When I tell you that many places actually have huge MINUS numbers today and others gigantic rises you will see this is no trivial tinkering.

Assuming there is not some undiscovered cock up (and with this testing and tracing who knows) Warrington has MINUS 126 cases today and Salford's Pop score goes up by the highest one in the history of the pandemic - over TWO HUNDRED! (though I bet it will not be the worst by the time I have finished). So literally anything could happen.
 
My wife has just come home
she has worked on ITU at Tameside all through this fucking shit
she's just told me me of yet another death
a bloke in his late 60's
2 relatives only allowed to go in has they switched his life support machine off

talk all about your number etc

I'v had to listen to all these personal stories since March now

Iv been on an early myself and been drinking,sorry for letting off steam
I can’t imagine how down you and your wife must be feeling, hope things improve for you both.
 
My wife has just come home
she has worked on ITU at Tameside all through this fucking shit
she's just told me me of yet another death
a bloke in his late 60's
2 relatives only allowed to go in has they switched his life support machine off

talk all about your number etc

I'v had to listen to all these personal stories since March now

Iv been on an early myself and been drinking,sorry for letting off steam
No problem mate , so many numbers banded about but they are people , this place didnt like me posting about the nurses and drs that died, giving them a name and some a face , very peculiar . Just a few hundred today like it is win , just the old and sick , hundreds of people lose family and loved ones, the numbers are people, never forget that , those unaffected so far are lucky
 
I do wonder what roads you are looking at because the traffic is far less than normal. An hour long commute is currently taking 30minutes including travelling a quarter of the m60 ring at “rush hour” and it is free flowing all the way.
I spend all day in my van around south manchester and into cheshire. Traffic nothing like what it was pre lockdown. Rarely hit any serious traffic. At worse its ‘heavy’ but where as before i would avoid certain roads at certain times, it makes no odds now.
can do the a6 from disley to stockport without hitting much traffic at all. Unheard of pre march

SO many of my customers work from home now, compared to very few/hardly any before
 
Just to say more. Might be a while as I work through the numbers today as they are utterly ludicrous based on the published data. The student farce has created utter utter chaos.

When I tell you that many places actually have huge MINUS numbers today and others gigantic rises you will see this is no trivial tinkering.

Assuming there is not some undiscovered cock up (and with this testing and tracing who knows) Warrington has MINUS 126 cases today and Salford's Pop score goes up by the highest one in the history of the pandemic - over TWO HUNDRED! (though I bet it will not be the worst by the time I have finished). So literally anything could happen.
What it actually means though is that the falls seen in Manchester and Nottingham in the last two weeks were even bigger. The falls tomorrow will also be spectacular no doubt. And to think, this is the data source they’ll be using to decide what to do next.........
 
No problem mate , so many numbers banded about but they are people , this place didnt like me posting about the nurses and drs that died, giving them a name and some a face , very peculiar . Just a few hundred today like it is win , just the old and sick , hundreds of people lose family and loved ones, the numbers are people, never forget that , those unaffected so far are lucky

Every person that dies is very sad but whether covid is here or not, it will still be happening. People have got so absorbed in this that they seem to forget that there are another 1,000 or so dying every day. No one is naming or giving them a face, not even a proper funeral at the moment.
 
The numbers in GM are utterly extraordinary - but then they are in other places too.

As you might expect it is really bad news for University towns as they have inherited thousands of cases that apparently went to places the students were not actually at. So if you were in halls in Manchester but came from London the number got allocated 200 miles away. Not saying that literally happened but it is the gist.

Goodness knows what the numbers will be like but I can tell you all big Uni towns are way up but by the looks of it Manchester will pay the heftiest price - and as a result todays GM total which will be about as believable as a cartoon. But hopefully is just a single day of nonsensical numbers.

Manchester (the city) went up today by 3174 cases and its pop score by an unheard of record of 574 in one go!

Meanwhile many places we thought were in big trouble are now not. With Wigan under 100. And three GM boroughs having NEGATIVE numbers of cases today. One of these in three figures!

Even if you do not normally read my scoreboard. When I post it in a while do so this time if only to be astonished.
 
No problem mate , so many numbers banded about but they are people , this place didnt like me posting about the nurses and drs that died, giving them a name and some a face , very peculiar . Just a few hundred today like it is win , just the old and sick , hundreds of people lose family and loved ones, the numbers are people, never forget that , those unaffected so far are lucky
every death is important
its a life
that is important to other lives
1 death ripples to hundreds,thousands

my wife is bame,but regardless does her duty every single shift.I'm so proud of her and scared for her too
 
Every person that dies is very sad but whether covid is here or not, it will still be happening. People have got so absorbed in this that they seem to forget that there are another 1,000 or so dying every day. No one is naming or giving them a face, not even a proper funeral at the moment.
Still just the flu eh, frontline workers literally died for their patients
 
I spend all day in my van around south manchester and into cheshire. Traffic nothing like what it was pre lockdown. Rarely hit any serious traffic. At worse its ‘heavy’ but where as before i would avoid certain roads at certain times, it makes no odds now.
can do the a6 from disley to stockport without hitting much traffic at all. Unheard of pre march

SO many of my customers work from home now, compared to very few/hardly any before
i drive buses for Arriva North East and driving round our region since the 2nd lockdown it appears to be busier now than pre lockdown. The lass who does our accounts says last Monday we took the highest number of passengers & money for over 2 years. No wonder the pandemic is going nowhere in the North East
 
I am so grateful to her and all the others , heroes to me , give her an extra cuddle

They are under such intense pressure. I know people in the nursing industry and it’s horrendous currently. My mum is in hospital and we are worried sick about her. She is non Covid but very poorly with breathing problems. She has been moved wards in the middle of the night to accommodate more Covid patients. I can hear the noise in the background when I phone and it sounds so intense. I don’t know how they do it. They deserve a medal. 170 plus people in Warrington hospital with Covid currently. 15 in ICU. 10 died at the weekend alone. The hospital is full to bursting. The stress must be incredible.
 
The South East added just 95 and the East ZERO today.

I am told they have reallocated lots of university students as nobody had a consistent plan on whether to count them as being located where they tested or where they lived!

Could be something to do with this.
 
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