COVID-19 — Coronavirus

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N Ireland 3 wks v 2 wks v last wk v TODAY Deaths / Cases/ 7 Day cases total / Patients / Ventilated

11d - 578c - 3535 - 452p - 37v

7d - 533c - 2421 - 456p - 32v

4d - 416c - 2601 - 435p - 29v

12d - 483c - 3031 - 425p - 24v - TODAY


As you see the circuit breaker worked better than in Wales and hospital numbers are still going down and cases rising only a little but the daily and weekly cases totals are going up not down. Just thankfully nowhere near the levels in they are in Wales.
 
mosssideblue said:
Maybe, if you don't like reading why people have concerns about the vaccine, you too could take your own advice and give the thread a miss.
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No because I’m not the one feeling I have to justify myself to people on a daily basis.

I genuinely (and I mean no offence) couldn’t give a fuck what happened to those that decide against it, so long as enough take it so that society achieves a level of herd immunity. So unlike you, I don’t take comments on this thread personally.
 
Stupid question, but just reading the posts about Leitch commenting that this second wave was almost entirely caused by different strains from different countries brought in over the summer, I take it the vaccines will be able to combat all of these strains and not just a particular one?
 
SWP's back said:
No because I’m not the one feeling I have to justify myself to people on a daily basis.

I genuinely (and I mean no offence) couldn’t give a fuck what happened to those that decide against it, so long as enough take it so that society achieves a level of herd immunity. So unlike you, I don’t take comments on this thread personally.
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Are you having a pop at the same posters calling out those with concerns and in your terms "every day".

I hope too that the majority who are able to have the vaccine accept it (including me), but I will defend my corner when someone wants to label me as something I am not (as I am sure you would).
 
ayrshire_blue said:
Stupid question, but just reading the posts about Leitch commenting that this second wave was almost entirely caused by different strains from different countries brought in over the summer, I take it the vaccines will be able to combat all of these strains and not just a particular one?
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The word strain appears to be often misused.

www.bioserendipity.com

Defining a New Strain of a Virus

Understand when a mutation leads to a new strain of a virus
www.bioserendipity.com www.bioserendipity.com

To date, the general view seems to be that there is no significant difference in immune response between the various virus mutations, and also that this type of virus mutates much more slowly than flu viruses, where different strains each winter require different vaccines.

How long it will be before a different vaccine might be required against an evolved strain seems unknown at present and hard to estimate

More speculatively, you could imagine that if a vaccine stops transmission of the current virus, that will put evolutionary pressure to mutate into a form resistant to the vaccine. A quick google reveals this is seen as a potential problem https://www.quantamagazine.org/how-vaccines-can-drive-pathogens-to-evolve-20180510/
 
roubaixtuesday said:
I posted a ink earlier to the FDA review of the Pfizer/BioNtech vaccine.

Turns out there's two versions on the FDA website - I *think* the one I posted earlier is a draft. The final version appears to be this one, for anyone interested in the detail.

https://www.fda.gov/media/144245/download
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Haven't had chance to read but is this for the clinical submission?
 
03 March 2002 said:
Haven't had chance to read but is this for the clinical submission?
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It's the Briefing doc for Vaccines and Related Biological Products Advisory Committee Meeting December 10, 2020

Benefit/Risk assessment covering safety and efficacy data from all clinical trials, to cover emergency use authorisation.
 
England hospital deaths today by date of occurrence:-

Note 33 of todays deaths were from more than 8 days ago. Though none earlier than mid October.

8 Dec adds 50 after 1 day (Last wk 55 added)

7 Dec adds 119 = 164 after 2 days (Last wk 139 added = 176)

6 Dec adds 54 = 231 after 3 days (Last wk 65 added = 258)

5 Dec adds 28 = 215 after 4 days (Last wk 44 added = 267)

4 Dec adds 28 = 259 after 5 days (Last wk 33 added = 256)

You can see week to week the add ons almost all are lower this week and the total after so many days is too bar the five day total.

215 is the lowest 4 day total for two weeks.

Of the other add ons two took dates just over 300, so there are now several with that. Including 29 Nov now at 303. But still nobody close to the 323 of 18 Nov that has again not increased today and remains the peak of this second wave.
 
Big increase today sadly.

All settings deaths 533.

Cases 16, 578. Biggest day to day rise since 24 November.
 
Yesterday 205, 315 tests led to 12, 282 cases at a positive rate of 6.0% positive.


And in cases from England - 175, 192 tests finding 10, 459 cases the result was almost identical at 6.0%


Today though the huge Welsh case load and high positivity there made a big difference


The UK numbers show there were 282, 132 tests and that found 16, 578 cases at 5.9% positive.


However just using England data there were 237, 698 tests finding 12, 960 cases at a 5.5% positive rate.
 
Healdplace said:
Yesterday 205, 315 tests led to 12, 282 cases at a positive rate of 6.0% positive.


And in cases from England - 175, 192 tests finding 10, 459 cases the result was almost identical at 6.0%


Today though the huge Welsh case load and high positivity there made a big difference


The UK numbers show there were 282, 132 tests and that found 16, 578 cases at 5.9% positive.


However just using England data there were 237, 698 tests finding 12, 960 cases at a 5.5% positive rate.
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In your opinion when will we start to see more positive news appear due to the vaccine?
 
Regional scoreboard - all up - but sadly the biggest increase today was in the North West

Looks like the good news might be ending at just the wrong time as we head towards Christmas

London - still top - at 2540 - up from 2203

Midlands - 1381 - up from 1065

North East - 687 - up from 406

Yorkshire - 1267 - up from 837. Second biggest rise today.

And North West up by 580 to 1734. This is the highest NW total in over 2 weeks. And the biggest rise in even longer.

.
 
Wythenshawe has been chosen as the first area in Manchester to start community based vaccinations from Tuesday 15 December.
People aged 80 and over will be first to receive the Covid vaccination.
Those eligible will get a letter or call from their GP.
More areas across the city will follow very soon
 
Keith Moncrieff said:
In your opinion when will we start to see more positive news appear due to the vaccine?
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I know you're not talking to me here, so apologies, but my guess is that we're looking at maybe towards the end of February for it start to take effect. The logistical challenges of 1) getting it to a lot of people and 2) getting people the second dose will take a while. It could be too the result of the vaccine is that deaths just stall, as opposed to go down, if that makes sense? We might carry on seeing 200-400 a day, where it could have been 500/600. It's gonna be very hard to tell possibly.
 
Keith Moncrieff said:
In your opinion when will we start to see more positive news appear due to the vaccine?
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Need millions to have had both doses and then a few weeks. So not any time soon sadly.

The problem is many will assume otherwise and drive things up over Christmas/New Year on the assumption it is not necessary quite so much now we have been 'saved'.

When at this time of year it is more important than ever.

The deaths might be the first thing to be obvious - unusually - as the ones getting the vaccine are the most likely to get really ill but the least likely to be spreading it.

Though if hospital spread can be curtailed by medical staff getting it that could be a gamechanger too in hospital or care home acquired numbers quicker than we might otherwise see.
 
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Healdplace said:
Need millions to have had both doses and then a few weeks. So not any time soon sadly.

The problem is many will assume otherwise and drive things up over Christmas/New Year on the assumption it i8s not necessary quite so much.

When at this time of year it is more important than ever.
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Yeah that's my fear. I've got a sinking feeling that Jan/Feb will be worse than November and December due to the inevitable Christmas spread/lockdown fatigue setting in/shite weather/vaccines relaxing people subconsciously. Hopefully i'm hugely wrong.
 
twosips said:
Yeah that's my fear. I've got a sinking feeling that Jan/Feb will be worse than November and December due to the inevitable Christmas spread/lockdown fatigue setting in/shite weather/vaccines relaxing people subconsciously. Hopefully i'm hugely wrong.
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We will end up in lockdown by mid/late Jan, once the 3 week lag from Xmas Day has kicked in.
 
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