Thinking about it for the last few days, we lost 1-0 to Arsenal in 2011/12 and we still won the league, we lost 3-2 to Liverpool in 2013/14 and we still won the league.
If we win on Monday we haven't won the league, similarly if we lose we haven't lost the league.
Like everyone else on here I would be very happy with a win but it doesn't guarantee anything.
The only thing I really want to see from us is get back to our early season work rate and a bit more aggressive defending from the front. It certainly won't magically fix all problems but it would certainly make us more difficult to play against.