Coronavirus (2021) thread

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Europe also slowing down in terms of vaccination rates. I think at last everyone is largely in agreement now, just a litle dispute on how quickly the controls are lifted. I don't actually understand why it makes such a big difference to hospitalisations and deaths but the models apparently suggest it does. Perhaps its because if you lift restrictions slowly you still have benefit from ongoing vaccination/infection, whereas if you do it one big bang, there's less opportunity for immunity to resist infection?

What's left for me is progress on new vaccines. I do hope that when we do the boosters we use up to date vaccinaes or we are going to get awfully tired with one vaccination after another. It's unlikely this is going to stop evolving so I think PHE would be wise to give max possible consideration to vaccinating with latest vaccines. I do accept though that they must have good reasons to do whatever they decide. As long as the whole thing is controlled by science and not the private profits of pharmaceutical companies, that's fine.
I think Marv, from the article you posted the other day, the key is that new vaccines need to go through clinical trials again so it’s not necessarily the easy option. You can’t just update the current ones. Memory serves me right Pfizer were looking to enter the trials with their updated vaccine in August but not sure how long it takes to get approval or whether it’s the same 6 months or so as previous.
 
New cases in the Netherlands down from 8,502 yesterday to 7,888, but hospitalisations up from 7 yesterday to 31. The R number was calculated to be 2.17 at the end of June, but it’s presumed to be even higher now.
 
I think Marv, from the article you posted the other day, the key is that new vaccines need to go through clinical trials again so it’s not necessarily the easy option. You can’t just update the current ones. Memory serves me right Pfizer were looking to enter the trials with their updated vaccine in August but not sure how long it takes to get approval or whether it’s the same 6 months or so as previous.
There's a Cov-boost trial underway I believe but I think it's largely using pre-existing vaccines. Moderna and GSK have their own trials that are underway based on SA variant. I think you are right trials are needed but I thought if a pre-existing vaccine had been distributed that they would be Phase I/II trials and not the very lengthy trials. We'll see.

Edit: I thought the Gods were smiling on me for a moment....

Just received an invite to Astrazeneca Beta Variant Booster trial. I tried to join it but they are over-subscribed.

Dear Mr Hagler,

You have received this email because you previously registered with the NHS COVID-19 Vaccine Research Registry.

Volunteers are needed to join a local COVID-19 clinical study researching vaccines against a COVID-19 virus variant.

Although approved COVID-19 vaccines are now available, it is not known how well these vaccines will work against mutated or ‘variant’ forms of the SARS-CoV-2 virus. Study AZD2816 is evaluating an investigational vaccine that has been designed specifically against the Beta variant of the SARS-CoV-2 virus, which first emerged in South Africa. The study is also evaluating the Oxford-AstraZeneca vaccine against the Beta variant. The vaccines in this study are being tested as a booster in people who have previously had a COVID-19 vaccine.

You may be able to participate in this study if you:

  • are 30 years of age or older
and

  • have received 2 doses of the Oxford-AstraZeneca, Pfizer-BioNTech, or Moderna COVID-19 vaccine.

Additional requirements may determine final eligibility.
 
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That sounds familiar. I was just suggesting that it could peak earlier in the North West. It's unlikely to proceed uniformly across the UK. I posted the Bolton and London cases up above somewhere and you can see quite a gap in time between the onset of the waves. I am expecting it to peak in Gtr Manchester before it peaks nationally but I haven't really got anything more to say than that. All guesswork.
All the data on GM and NW I have been posting daily for weeks here shows that GM was a MUCH bigger factor at the start of this wave in the NW region numbers and has fallen a lot since.

From around 75% of the cases at one stage to 42% now.

It has flattened off aound here as this is about its base number wave or not gven population.

There is no question this wave is not going to be all in and all out at once. Even across the NW - let alone the regions still climbing up to their peak and catching the NW daily now. Yorkshire and London especially. Even the tiny North East is uncomfortably close to North West numbers as it keeps going up.

How Bolton has changed day to day since April shows that. Though it is stubbornly still above where it should be it went from worst to best in GM in weeks. And is the ONLY borough now not with a Pop score 400 or above. Even Bury broke that barrier yesterday and Stockport did a few days ago.

Bolton IS rising too though, But way behind Oldham and Rochdale the two worst GM boroughs.

Bolton 343 versus Oldham 640.

Bolton topped out at 456 on 23 May.

Only Bolton. Bury and Stockport are currently below the highest Pop number Bolton reached!
 
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I think Marv, from the article you posted the other day, the key is that new vaccines need to go through clinical trials again so it’s not necessarily the easy option. You can’t just update the current ones. Memory serves me right Pfizer were looking to enter the trials with their updated vaccine in August but not sure how long it takes to get approval or whether it’s the same 6 months or so as previous.
Won't it be like flu vaccines. I don't think they update them until the summer and have them ready for October roll out.
 
That sounds familiar. I was just suggesting that it could peak earlier in the North West. It's unlikely to proceed uniformly across the UK. I posted the Bolton and London cases up above somewhere and you can see quite a gap in time between the onset of the waves. I am expecting it to peak in Gtr Manchester before it peaks nationally but I haven't really got anything more to say than that. All guesswork.

Sounds reasonable. I'd only heard one date which I assume was national, which pretty much equates to London given the numbers posted.
 
Northern Ireland data

0 deaths - was 0 last week

511 cases - was 417 last week


That is it again today.

It will be back to normal weekday reporting here tomorrow.
 
So total deaths today 42 - with England out of hospital to come. Last week it was 39 at this stage. So only a modest rise on usually the worst day of the week with weekend catch up add ons.

That 39 became 37 on all settings later. Possibly 1 of today's England deaths will be deducted due to age of the case too.
 
And the three nation cases today are:- 3777

It was 3478 last week.

England later added 25, 295 to total 28,773


Yesterday England added 30, 619 to the other nations total of 3852 to total 34, 471
 
Zoe App Data:

THIS IS STILL GOING IN THE RIGHT DIRECTION

Predicted cases DOWN 815 to 32, 424 - it has been around 32/33K for over a week now.

Ongoing symptomatic cases 454, 600 - up just 1243 - it was rising in 5 figures a week ago,
 
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