COVID-19 — Coronavirus

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BlueAnorak said:
Vaccines always have some ADRs.
Having an AI application to analyse ADRs from a multitude of vaccines seems eminently sensible to me
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They may be looking for an AI application tool, however knowing the way such adverts are written I doubt that they would include such specific information as part of the brief to attract bidders.
 
Healdplace said:
Btw great news for the North West hospitals today. We stayed over the peak of wave 1 patient numbers that Sky were referring to earlier for one day. And - for now - are back under it.

Patients down 2948 to 2781 today so back 109 below the peak. This is actually LESS patients than 7 days ago when it was 2845. The first time that has happened over 7 days for some weeks.

Ventilators also down from 259 to 229 - again LESS than the 238 on them a week ago.

The NE/Yorkshire health area continues to now have more patients in than the NW which only happened a few days ago for the first time in the second wave.

This is all good news, It can change and yes the many deaths here are a factor but it is hard not to see these as positives.
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Well the bad news is that about a third of the number decrease will be down to deaths. But the good news is that the people are not being replaced on the meat grinder conveyor belt.
 
inbetween said:
Transportation is okay but keeping the vaccine stable within doctors surgeries and so on where the vaccine could be administered will be problematic. It's the scale that's the problem as I suppose your local doctors will not be able to store thousands of doses at -70c.

It seems obvious that the best way to administer the vaccine is by doing it centrally, maybe with the army helping which sounds to be the plan. The government has a very poor record on managing things so far though so it just looks like a car crash waiting to happen.

We'll see anyway but indeed we do have to hope and be optimistic that it works out.
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I was watching the BBC news channel last night and the pfizer vaccine will last 5 days in a fridge once out of the freezer. So that makes distribution easier.
The Oxford vaccine just needs to be stored in a fridge But of the best 6 vaccine candidates on the conveyer belt half of them need to be supper cooled.
All good news for companies that can sell -80⁰C portable freezers
 
discussion point; why are we spending £40bn on a mass testing programme?

Why not just treat and test those who need to come to hospital? why bother testing the populace at large?

so we can find the hotspots and clamp down? well, given that every single reactionary policy has come as the case numbers have been falling, as in Liverpool, Manchester, Lancashire, London didnt even rise, then i'd say they've been a bit pointless.

why not spend £40bn on other public health like nurses, clinics, ICU beds etc.

i've become very jaded with the testing programme, it seems like a LOT of public money being thrown after something that wont change much - those who need to go to hospital will.
 
shemnel said:
discussion point; why are we spending £40bn on a mass testing programme?

Why not just treat and test those who need to come to hospital? why bother testing the populace at large?

so we can find the hotspots and clamp down? well, given that every single reactionary policy has come as the case numbers have been falling, as in Liverpool, Manchester, Lancashire, London didnt even rise, then i'd say they've been a bit pointless.

why not spend £40bn on other public health like nurses, clinics, ICU beds etc.

i've become very jaded with the testing programme, it seems like a LOT of public money being thrown after something that wont change much - those who need to go to hospital will.
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To be fair, track and trace and testing etc can help a bit when done properly. Just seen a real world example myself. My best friend and his partner are both avid gym goers and were both working in offices. His missus got a track and trace notification about being in contact with someone with covid.

She said initially she was a bit frustrated as she thought she'd be fine and was disappointed that she couldn't be up and about, working in the office, going gym etc, but she stayed at home - my mate decided to stay at home too... thankfully they did as a few days later they both came down with it. Both had a test. Positive. Both felt like shite for a couple of weeks, but both thankfully okay now.

I was speaking to them last night and they said tbh it was a good job track and trace actually worked for them as they would have gone to a couple more gym classes each, gone into offices, restaurants etc. Almost certainly spread it onto people. My mate's dad has a serious disability too so he simply has to pop around and help him sometimes. He could have seen him or anything.

Now the T&T has been a bit of a shambles, but it's obvious that when it works it can be very very useful. I don't think its a stretch to say that they could have inadvertently passed it on to loads of people, potentially killing someone, if they hadn't been gotten in touch with. I can imagine there's a very similar principle for the mass testing too. I agree its flawed, but there are clear potential benefits too.
 
Question if anybody knows the answer as I can't seem to find what I need to know and wondered if anybody has any idea?

Daughters class at primary school has been sent home this morning. Me and her mother have shared custody and its fallen on a day she has dropped her off so has now gone home with her.

Does my daughter now have to stay at her mothers house for the next 14 days or are we still able to use two homes? I did the drop offs Monday and Tuesday so it's not like I haven't seen my daughter since last week.

What a shitshow.
 
BlueAnorak said:
I was watching the BBC news channel last night and the pfizer vaccine will last 5 days in a fridge once out of the freezer. So that makes distribution easier.
The Oxford vaccine just needs to be stored in a fridge But of the best 6 vaccine candidates on the conveyer belt half of them need to be supper cooled.
All good news for companies that can sell -80⁰C portable freezers
Click to expand...

Thanks. That answers one of my big questions. if it only lasted an hour then it made things very tricky!.
 
Nick_1985 said:
Question if anybody knows the answer as I can't seem to find what I need to know and wondered if anybody has any idea?

Daughters class at primary school has been sent home this morning. Me and her mother have shared custody and its fallen on a day she has dropped her off so has now gone home with her.

Does my daughter now have to stay at her mothers house for the next 14 days or are we still able to use two homes? I did the drop offs Monday and Tuesday so it's not like I haven't seen my daughter since last week.

What a shitshow.
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From the guidance she should stay in one place for the whole time, as she shouldnt leave the house. How old is she?

How to self-isolate​

You must not leave your home if you're self-isolating.

Don’t​

  • do not go to work, school or public places – work from home if you can
  • do not go on public transport or use taxis
  • do not go out to get food and medicine – order it online or by phone, or ask someone to bring it to your home
  • do not have visitors in your home, including friends and family – except for people providing essential care
  • do not go out to exercise – exercise at home or in your garden, if you have one
 
shemnel said:
discussion point; why are we spending £40bn on a mass testing programme?

Why not just treat and test those who need to come to hospital? why bother testing the populace at large?

so we can find the hotspots and clamp down? well, given that every single reactionary policy has come as the case numbers have been falling, as in Liverpool, Manchester, Lancashire, London didnt even rise, then i'd say they've been a bit pointless.

why not spend £40bn on other public health like nurses, clinics, ICU beds etc.

i've become very jaded with the testing programme, it seems like a LOT of public money being thrown after something that wont change much - those who need to go to hospital will.
Click to expand...

there are a few points for me,

1) is just raw data knowing a pretty much exact figure of how many people in the population have it. Id like to see them do antibody tests too at this point to get a really clear view of it.

2) testing a whole population of a city you will catch pretty much all cases, symptomatic or not ( as well as some who have had it and cleared it but still have remnants of the virus in there system.

that will allow for everyone to really know they need to isolate for the 2 weeks and in theory 2/3 weeks after testing the whole city you end up with cases plummeting as in theory you catch pretty much all cases and stop them there and then.

of course this depends on people doing the right thing if they get a diagnosis.
 
Nick_1985 said:
Question if anybody knows the answer as I can't seem to find what I need to know and wondered if anybody has any idea?

Daughters class at primary school has been sent home this morning. Me and her mother have shared custody and its fallen on a day she has dropped her off so has now gone home with her.

Does my daughter now have to stay at her mothers house for the next 14 days or are we still able to use two homes? I did the drop offs Monday and Tuesday so it's not like I haven't seen my daughter since last week.

What a shitshow.
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Yes she needs to stay with her mum, that is what isolating is
 
Not particularly anti-vax responses (but likely falling into vaccine nationalism) but news of Pfizer 'winning the race' (so far and conscious nothing is certain atm) but there's a lot of 'evil Pfizer/Big Pharma companies' concerned about nothing more than share prices and profit going around at the moment.

I know the US healthcare system is highly complex but from what I've read, much of the profits are fed back into even more research (and as insurance over drugs or vaccines that never quite make it).

Neither singing the praises of Pfizer nor suggesting they're the anti-christ, I was wondering of you guys and gals opinions.
Are AZ any different (given the price of Pfizer's £29 per vaccine to AZ's £2 per shot?)

There's a book by the virilogist Peter Kolchinksky (linked below) which I may go ahead and buy.

Amazon product ASIN 1733058915
 
somapop said:
Not particularly anti-vax responses (but likely falling into vaccine nationalism) but news of Pfizer 'winning the race' (so far and conscious nothing is certain atm) but there's a lot of 'evil Pfizer/Big Pharma companies' concerned about nothing more than share prices and profit going around at the moment.

I know the US healthcare system is highly complex but from what I've read, much of the profits are fed back into even more research (and as insurance over drugs or vaccines that never quite make it).

Neither singing the praises of Pfizer nor suggesting they're the anti-christ, I was wondering of you guys and gals opinions.
Are AZ any different (given the price of Pfizer's £29 per vaccine to AZ's £2 per shot?)

There's a book by the virilogist Peter Kolchinksky (linked below) which I may go ahead and buy.

Amazon product ASIN 1733058915
Click to expand...
Pharma companies are not charities, they make money , a lot goes back into finding new drugs , they make losses on potential drugs that never make it to market , there are many of those every year

The scientists at these companies want to do what all of them do and that is make vaccines to save people and other drugs to make peoples lives better
 
shemnel said:
ok, some data re the new lateral flow test being used in Liverpool;

Sensitivity 76.8% for all PCR-positive individuals but detects over 95% of individuals with high viral loads
Specificity of 99.68%

Detection limit roughly equivalent to 25 Ct in PCR test

www.gov.uk

Oxford University and PHE confirm high-sensitivity of lateral flow tests

Extensive clinical evaluation shows lateral flow tests are accurate and sensitive enough to be used in the community, including for asymptomatic people.
www.gov.uk www.gov.uk


today in Liverpool; 44k tests and 220 positive, rate of 0.5%

this is still being pushed to those without symptoms.

This is important context;

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Just wondering - are these the only tests being done in Liverpool now? Or just extra ones being included in the official daily case data on gov.uk? Or listed separately altogether?

As they are quick response tests they will all presumably be reported on the day.

I ask as the Liverpool cases shown for last night by Gov.UK were 201. Will these 220 be the numbers for today perhaps.

Or are they still doing other tests?

Liverpool's positive case numbers over past 4 days published on Gov UK were 185 - 186 - 165 - 201
 
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