The only thing that I'm on my guard about is someone getting another bad injury from a dead rubber like this. That would be utterly stupid (same for red card, though that's more unlikely). There is no way on God's earth that West Ham are going to put six past us, unless we make up a team from the posters on this thread (I'm in nets) and even then I think we'd nick an away goal.
As an earlier poster cannily put it. Three principles: rest those who badly need it (Negredo a definite for that, also Yaya, in my opinion, probably Silva as well). Give those who desperately need playing time the necessary: Richards and Jovetic definites, maybe even Rodwell. And win this thing, because I don't like seeing us lose. Ever.