Autophagy (and fasting).

[somapop]

Think he’s specifically talking about IF rather than Autophagy PC ?

The two subjects need splitting on this thread imo, whilst there are undoubted parallels and similarities, Autophagy is very specific, black and white, IF, you get a bit of leeway and isn’t conducive to achieve Autophagy (although still it’s an energy in/energy out process if IF is for weight/fat loss .

This is where I'm not entirely clear on (and is the science supportive enough yet to encourage the practice etc).

I'm definitely lost a bit of weight since starting IF. This is in conjunction with a step up in my gym routines too.
I'm doing the 8 hour window and I've pretty much stuck to that (11 - 7 or 12 - 8 generally).
I don't even have black coffee first thing (that's another side subject!)

But I"m still fighting fatigue (and I was a little before I started tbf) which I need to get to the bottom off. It's not like I'm eating that much less (literally skipping that small bowl of oats and bran I used to have and just moving the fruit I had for breakfast up to 11/12am).
From what I've read it came take a fair amount of time to adjust.

I've a feeling with the increase in gym time I'm not pushing enough protein in so I've succumbed to whey protein powder this week as a trial.

Eating way earlier in the evening has to be beneficial though (certainly for sleep).

 

[Dirty Harry]

This is where I'm not entirely clear on (and is the science supportive enough yet to encourage the practice etc).

I'm definitely lost a bit of weight since starting IF. This is in conjunction with a step up in my gym routines too.
I'm doing the 8 hour window and I've pretty much stuck to that (11 - 7 or 12 - 8 generally).
I don't even have black coffee first thing (that's another side subject!)

But I"m still fighting fatigue (and I was a little before I started tbf) which I need to get to the bottom off. It's not like I'm eating that much less (literally skipping that small bowl of oats and bran I used to have and just moving the fruit I had for breakfast up to 11/12am).
From what I've read it came take a fair amount of time to adjust.

I've a feeling with the increase in gym time I'm not pushing enough protein in so I've succumbed to whey protein powder this week as a trial.

Eating way earlier in the evening has to be beneficial though (certainly for sleep).

With Autophagy, I think there’s a decent body of evidence and backed by some highly respected people in the field, so I think it’s safe to say there’s plenty of support, whether that changes in 10-20 years time who knows, science is always ‘on the move’ so to speak.

Just remember mate, IF isn’t a magic bullet when it comes to weight/fat loss, it’s just a method to control energy balance, some people get on with it, some don’t, what exactly are your goals anyway ?

 

[Deleted member 77198]

This is where I'm not entirely clear on (and is the science supportive enough yet to encourage the practice etc).

I'm definitely lost a bit of weight since starting IF. This is in conjunction with a step up in my gym routines too.
I'm doing the 8 hour window and I've pretty much stuck to that (11 - 7 or 12 - 8 generally).
I don't even have black coffee first thing (that's another side subject!)

But I"m still fighting fatigue (and I was a little before I started tbf) which I need to get to the bottom off. It's not like I'm eating that much less (literally skipping that small bowl of oats and bran I used to have and just moving the fruit I had for breakfast up to 11/12am).
From what I've read it came take a fair amount of time to adjust.

I've a feeling with the increase in gym time I'm not pushing enough protein in so I've succumbed to whey protein powder this week as a trial.

Eating way earlier in the evening has to be beneficial though (certainly for sleep).

I’ve been in hospital a lot recently with a PE, but something I found from the dozens of blood tests they did on me was that I had an enzyme being produced in higher quantities than ideal because I have a fatty liver and they’ve told me it will be good for me to reduce my visceral fat which can eventually reduce the fat in the liver.

They said that enzyme (I’ll try and remember the name of it if I can) and the fatty liver in general can cause a fatigue and general malaise.

 

[somapop]

With Autophagy, I think there’s a decent body of evidence and backed by some highly respected people in the field, so I think it’s safe to say there’s plenty of support, whether that changes in 10-20 years time who knows, science is always ‘on the move’ so to speak.

Just remember mate, IF isn’t a magic bullet when it comes to weight/fat loss, it’s just a method to control energy balance, some people get on with it, some don’t, what exactly are your goals anyway ?

Yeah, from what I've read (and where the sources behind the research) it all seems positive.
I've shed a few pounds and feel physically lighter/bouncier but still can't shake off this fatigue.

Can't put my finger on it as I'm not really eating any less as mentioned above. Anecdotally it seems it takes a while for this to level out (and I've the added variable of increasing gym work - deadlifting/weights amongst the yoga, pilates and weekend run).

Goals were:

* Shift a few excess pounds (although I train every day and don't over eat and generally eat healthily, I also have a desk job....and visit the office just once a week, so I'm quite stationary).
Cutting out some calories I won't burn can't be a bad thing.

* Eat earlier in the evening. I was eating past 10pm most evenings and this may in turn have affected my sleep (which is another issue)

* Interest in Autophagy and how this may benefit ones health for a variety of reasons (decrease inflammation, cell repair). This last one if the element I'd have to run with in good faith alone at this stage.

 

[somapop]

I’ve been in hospital a lot recently with a PE, but something I found from the dozens of blood tests they did on me was that I had an enzyme being produced in higher quantities than ideal because I have a fatty liver and they’ve told me it will be good for me to reduce my visceral fat which can eventually reduce the fat in the liver.

They said that enzyme (I’ll try and remember the name of it if I can) and the fatty liver in general can cause a fatigue and general malaise.

Sorry to hear that mate and hope you manage to pick up a bit.

I'm far for overweight but still carrying surplus but that's down to minimal now. Could do with carrying on with weight training, yoga and pilates for overall strength which puts me on good stead (yoga and pilates have both been incredibly for my fitness, strength and well being).

But of late (and to reiterate, this started before I began IF/TRE) I've had this fairly intense fatigue this year. But sleep is a big factor. Take last night: work social, just two beers and home my ten (bed at 10:30). I was awake ALL night till my alarm went off.

That 'rest is as good as sleep' is utter carnage of a statement. I'm zoinked today.

 

[Deleted member 77198]

Sorry to hear that mate and hope you manage to pick up a bit.

I'm far for overweight but still carrying surplus but that's down to minimal now. Could do with carrying on with weight training, yoga and pilates for overall strength which puts me on good stead (yoga and pilates have both been incredibly for my fitness, strength and well being).

But of late (and to reiterate, this started before I began IF/TRE) I've had this fairly intense fatigue this year. But sleep is a big factor. Take last night: work social, just two beers and home my ten (bed at 10:30). I was awake ALL night till my alarm went off.

That 'rest is as good as sleep' is utter carnage of a statement. I'm zoinked today.

Thanks mate!

Yeah sleep is massive. An ex of mine said I used to stop breathing in my sleep for ten seconds at a time and then wake myself up with a big gasp for air. I noticed I was knackered a lot despite being the fittest I’ve ever been working in gyms so went to the Doc who I had sleep apnea so could wake up a few dozen times a night without realising and may never even enter a deep sleep some nights or even any nights.

I’m the same, im in fairly decent shape for a 40 year old, but I’m a unit (6’4” and 19stone). I actually got into good shape over lockdowns as I had been over 20stone (as high as 21stone) for a good few years and I did drink a lot for many years so my liver took a beating.

Good thing is the liver can recover if I change my lifestyle and I’m going to try IF to shift this visceral fat and liver fat. Unfortunately, from the PE part of my lung has died and that’s never coming back but the liver is a bit of a magician in that it can replenish itself when looked after and I’ve been quite interested in reading about autophagy since this thread popped up so hopefully it can all aid in sorting my problems out.

 

[somapop]

Thanks mate!

Yeah sleep is massive. An ex of mine said I used to stop breathing in my sleep for ten seconds at a time and then wake myself up with a big gasp for air. I noticed I was knackered a lot despite being the courtesy of ever been working in gyms so went to the Doc who I had sleep apnea so could wake up a few dozen times a night without realising and may never even enter a deep sleep some nights or even any nights.

I’m the same, im in fairly decent shape for a 40 year old, but I’m a unit (6’4” and 19stone). I actually got into good shape over lockdowns as I had been over 20stone (as high as 21stone) for a good few years and I did drink a lot for many years so my liver took a beating.

Good thing is the liver can recover if I change my lifestyle and I’m going to try IF to shift this visceral fat and liver fat. Unfortunately, from the PE part of my lung has died and that’s never coming back but the liver is a bit of a magician in that it can replenish itself when looked after and I’ve been quite interested in reading about autophagy since this thread popped up so hopefully it can all aid in sorting my problems out.

Ahh - hope you see some improvements your health.

I tend to feel way better when I'm carrying less weight. I've fortunately managed to keep it in check over the past few years but following a really awful bout of Covid then almost a year of long Covid (when I could barely climb stairs never mind run) I piled a fair bit on again. Took a good while to get back in shape, but TRE/IF seems to be shifting that surplus stuff quite well.
Having a strong core (through lifting, yoga and pilates) has been incredibly beneficial too. Gives you that youthful vitality (and there was a time I could barely walk without doubled up with back pain and that was a psychological low point for me)

I'm quite good at new routines (think that's the OCD in me working for the good this time).
Let us know how you get on - I'm definitely interested on how other people get on with it.
Keen to know how your energy is on the routine.

 

[Deleted member 77198]

Ahh - hope you see some improvements your health.

I tend to feel way better when I'm carrying less weight. I've fortunately managed to keep it in check over the past few years but following a really awful bout of Covid then almost a year of long Covid (when I could barely climb stairs never mind run) I piled a fair bit on again. Took a good while to get back in shape, but TRE/IF seems to be shifting that surplus stuff quite well.
Having a strong core (through lifting, yoga and pilates) has been incredibly beneficial too. Gives you that youthful vitality (and there was a time I could barely walk without doubled up with back pain and that was a psychological low point for me)

I'm quite good at new routines (think that's the OCD in me working for the good this time).
Let us know how you get on - I'm definitely interested on how other people get on with it.
Keen to know how your energy is on the routine.

Yeah I’ve not done any exercise since the embolism so starting to feel sluggish and clothes are tight. So this is where it begins!

At my mass I can lose weight and a lot of it in a short space of time. But I want to get back to my lockdown level where I lost a few stone and kept it off for a good while.

 

[paulsimpson]

I’m not sure you can reach/maintain autophagy if you have tea and milk during the fasting hours.

Well I'm not trying to reach Autopagy . You will not enter autophagy unless you take only water or black tea over 24 hours+. But that's not necessary for weight loss. The 16 hours intermittent fasting stops the insulin from spiking and allows for weight loss over a long period of months until optimal weight is reached and one doesn't lose or gain any more weight. Provided you stay off excess carbs the optimal weight can be maintained for years.
I took a mini break away last week and didn't do the fast . I gained about 2- 3 lbs but this week am now back to my 16 hour fast/ 8 hours( where I eat a good breakfast and Dinner. Sometimes I'll even squeeze in a third meal/ snack ) and will lose those lbs in the next 2 weeks.

 

[MadchesterCity]

Well I'm not trying to reach Autopagy . You will not enter autophagy unless you take only water or black tea over 24 hours+. But that's not necessary for weight loss. The 16 hours intermittent fasting stops the insulin from spiking and allows for weight loss over a long period of months until optimal weight is reached and one doesn't lose or gain any more weight. Provided you stay off excess carbs the optimal weight can be maintained for years.
I took a mini break away last week and didn't do the fast . I gained about 2- 3 lbs but this week am now back to my 16 hour fast/ 8 hours( where I eat a good breakfast and Dinner. Sometimes I'll even squeeze in a third meal/ snack ) and will lose those lbs in the next 2 weeks.

Have you tried KETO OMAD 23/1 before?