Coronavirus (2021) thread

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west didsblue said:
Neither would your missus if the baby's due in September, unless she's not human and is a species that has an 8 week pregnancy cycle.
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Still don’t understand you, my missus hasn’t have the vaccine, she couldn’t have had the vaccine even if she wanted it (which we didn’t) in Jan.

I’m saying there is no way to know it’s safe yet for fetuses who’s mother or father have been vaccinated, I do think it is highly likely to be safe by the way, but why would anyone take the risk yet if they’ve already had covid and were ok. I get it if your high risk as you might not see the birth through.
 
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bluesteel said:
I’m saying there is no way to know it’s safe yet for fetuses who’s mother or father have been vaccinated
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Despite having been shown the evidence for mothers.

As to fathers - you're implying that vaccination damages sperm? I think you're way down the rabbit hole here.
 
bluesteel said:
Still don’t understand you, my missus hasn’t have the vaccine, she couldn’t have had the vaccine even if she wanted it (which we didn’t) in Jan.

I’m saying there is no way to know it’s safe yet for fetuses who’s mother or father have been vaccinated, I do think it is highly likely to be safe by the way, but why would anyone take the risk yet if they’ve already had covid and were ok. I get it if your high risk as you might not see the birth through.
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Most of the trials were done on women who were vaccinated whilst already already pregnant. As has been spelt out on a few occasions, just because she's had Covid that doesn't make her immune from catching another variant and the chances of Covid causing pregnancy complications is much higher than problems arising due to having the vaccine. So you are both really taking a chance, and you are putting your unborn child at greater risk as well.
 
grunge said:
Not exactly a protocal override there tho is it. the phases were still done. at most the people in the next phases of trials may have been at a bit more risk, the end product has had the same level as trials as any other.

if its mRNA your worried about, AZ and JnJ are not mRNA and are both fully approved by the UK medical board. As has Pfizer and Moderna mind you which are mRNA ones.

Why is FDA approval more important than the UK medical boards?
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The end product isn’t the same, sorry, you can’t say x happened to y % of people who took the vaccine over a z period in trial! It’s why it’s still only emergency approved over half a year later!!

In regards to the FDA, mainly because of the suing culture in the US and therefore the tendency to get it right (I personally reckon they’ll drag it out a bit for the reasons stated above) and they’ll almost definitely have a bigger budget (bit as we know in footy that doesn’t alway matter though :) ).
 
Northern Ireland data:

FIRST DATA SINCE FRIDAY OTHER THAN CASE NUMBERS & DEATHS

1 death - was 0 last week

636 cases - was 570 last week

3977 weekly rolling cases total - was 3432 last report Friday - 3054 last week

16 care home outbreaks - was 8 last week - BIG concern over these doubling

72 patients - up from 60 last report Friday & 43 last week

1 ventilated - up from 0 Friday and 1 last week
 
True_Blue69 said:
You should be quoting pandemrix rather than Thalidomide. Swine flu vaccine that has caused narcolepsy, not sure what the trials were but more relevant than Thalidomide.
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There will be loads I don’t know about, the only reason mentioned that was because of the potential impact on kids which is impossible to have been tested properly, just as one example.
 
bluesteel said:
The end product isn’t the same, sorry, you can’t say x happened to y % of people who took the vaccine over a z period in trial! It’s why it’s still only emergency approved over half a year later!!

In regards to the FDA, mainly because of the suing culture in the US and therefore the tendency to get it right (I personally reckon they’ll drag it out a bit for the reasons stated above) and they’ll almost definitely have a bigger budget (bit as we know in footy that doesn’t alway matter though :) ).
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Read up on Trial phases. they are not a tick sheet where 1 needs to be done before the other, they are different demographic groups for different data sets ( recommended doses vs more/less dose etc with different levels of age/illnesses in the demographics ). and they are not for lengthening test durations. at most the length of time of trials and delays between trial phases is a side effect of lack of funding.

The only trial that really needs to come 1st is trial 0 which is animal testing, and maybe some of phase 1 which is a key safety check before moving to larger group stage 2/3 trials

Doing the end of phase 1 and phase 2/3 at the same time is perfectly valid. its only seen as unusual as there is never funding in place to do it.

www.concertpharma.com

Understanding Clinical Trial Terminology: What’s a Phase 1, 2 or 3 Clinical Trial? - Concert Pharmaceuticals

While preclinical research that is done in a lab can provide foundation information about how a drug may work and its safety, it is not a substitute for studies that show how the drug will interact with the human body. The term “clinical trials” or “clinical research” refers to studies that are...
www.concertpharma.com www.concertpharma.com
 
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NORTHERN IRELAND 7 DAYS CASES BY AGE

0 - 19 (1119) 28.2%

20 - 39 (1800) 45.3%

40 - 59 (791) 19.9%

60 - 79 (233) 5.8%

80 PLUS (32) 0.8%

THIS PATTERN IS PRETTY STEADY NOW AND THE AGE RANGE MOST CATCHING IT IS VERY CLEAR.

THE RISE IN 60 - 79 IS THE ONLY CONCERN BUT IT IS SLOW NOT RAPID IN NY ESCALATION.
 
bluesteel said:
The end product isn’t the same, sorry, you can’t say x happened to y % of people who took the vaccine over a z period in trial! It’s why it’s still only emergency approved over half a year later!!

In regards to the FDA, mainly because of the suing culture in the US and therefore the tendency to get it right (I personally reckon they’ll drag it out a bit for the reasons stated above) and they’ll almost definitely have a bigger budget (bit as we know in footy that doesn’t alway matter though :) ).
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I've had a glance over the terms of the EUA from the MHRA and I can't see anything that I haven't been expected to include in a formal submission. If anything the EUA dictates a more stringent release protocol (individual batch release assessments).

The FDA are definitely not one of the most difficult jurisdictions to satisfy.
 
ENGLAND HOSPITL ADMISSIONS DATA

GOOD NEWS IN THE NORTH WEST

Admissions (on Monday recall so usually up from weekend lag)

610 - up from 502 Sunday and 416 last Monday

North West admissions DOWN - 105 - was 114 last Monday,

As expected the other regions are now starting to overtake the NW

London up from 55 to 96

Midlands up from 81 to 122

NE & Yorkshire up from 95 to 142 - Much the highest today, And now where NW sadly was for past few weeks

NW the only region going down. All be it very slowly but enough to be overtaken by two other regions and close to a third doing so any day.
 
Having a nightmare here Need to vent

My wife attended her brothers wedding on Saturday and has now been told she has to self isolate. Turns out her mum had seen her sister (who tested positive on Friday) the day before and decided to lie to my wife and said she hadn’t seen her went to the fucking wedding and now her mum has also tested positive and infected god knows how many.

Due my second jab Friday so hoping I don’t get it we are all testing negative at the moment. she was holding my 18 month old son as well as my 5 year old who suffers with asthma. To say I’m not happy is an understatement and to top it all she called me disrespectful as I said she was selfish as it doesn’t just effect her family!

My very vulnerable mum looks after our children when we are at work so now she has potentially been exposed as has my dad who has met numerous elderly clients over last few days blissfully unaware my mother in law is such a selfish twat. Not great fun either trying to test two young children poor bastards.

They have been flouting the rules the whole time and I bit my tongue but I fucking lost it with her today still absolutely furious
 
DMA's said:
Having a nightmare here Need to vent

My wife attended her brothers wedding on Saturday and has now been told she has to self isolate. Turns out her mum had seen her sister (who tested positive on Friday) the day before and decided to lie to my wife and said she hadn’t seen her and instead went to the fucking wedding and now she has also tested positive and infected god knows how many.

Due my second jab Friday so hoping I don’t get it we are all testing negative at the moment. she was holding my 18 month old son as well as my 5 year old who suffers with asthma. To say I’m not happy is an understatement and to top it all she called me disrespectful as I said she was selfish as it doesn’t just effect her family!

My very vulnerable mum looks after our children when we are at work so now she has potentially been exposed as has my dad who has met numerous elderly clients over last few days blissfully unaware my mother in law is such a selfish twat. Not great fun either trying to test two young children poor bastards.

They have been flouting the rules the whole time and I bit my tongue but I fucking lost it with her today still absolutely furious
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Chances are if she caught it only the day before the wedding it's unlikely she was infectious at the wedding. Most sources say the incubation period is from 2 to 14 days. Can understand your anger though.
 
ENGLAND HOSPITAL DATA PATIENTS

Total up 140 to 3110.

Last Wednesday numbers rose by 146 to 2144

Regions: Change since yesterday and V was Last Wednesday

EAST UP 3 to 154 - was 105

LONDON UP 26 to 540 - was 397

MIDLANDS UP 76 to 601 - was 375 - MIDLANDS RAPIDLY FOLLOWING NE & YORKS AS NEXT BIG UPTICK REGION

NE & YORKSHIRE UP 14 to 657 - was 420 - BIG WEEK TO WEEK RISE

SOUTH EAST UP 21 to 227 - was 143

SOUTH WEST UP 1 to 160 - was 104


AS FOR THE NORTH WEST:-

DOWN 1 to 771 - was 600


Only by 1 but not only lower admissions Monday but the only region with net fall in patient numbers today.

This is a hopeful sign.
 
ENGLAND HOSPITAL DATA VENTILATORS

Total UP 19 to 489

Last Wednesday numbers rose by 24 to 377


Regions: Change since yesterday and V was Last Wednesday


EAST UP 4 to 30 - was 18

LONDON UP 11 to 112 - was 74

MIDLANDS UP 6 to 90 - was 64

NE & YORKSHIRE UP 1 to 85 - was 66

SOUTH EAST UP 2 to 32 - was 19

SOUTH WEST STAYS AT 19 - was 13


AS FOR THE NORTH WEST:-

DOWN 5 to 121 - was 123


The only region to fall and also down week to week. When others are clearly rising,

Just one day and it might change but these trends in the NW right now are looking hopeful.
 
Still no full data due to rhe processing problem but they have posted on Gov UK THIS basic note of numbers

All settings deaths 49

Cases 42, 302 - a pretty big rise unfortunately.

Yesterday was 36, 660 and last Wednesday 32, 548

More later when they do update.

But we are clearly now seeing the rise in hospital numbers and cases driven by all the other regions coming up to the full power of Delta a few weeks behind the NW and Scotland.

More deaths will inevitably follow as the last link in the chain.
 
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