COVID-19 — Coronavirus

[mosssideblue]

Had my flu jab today, the nurse said they didn't have storage facilities at the temp needed

This is what I asked, but it seems our resident itk, is satisfied we don't need to

 

[Healdplace]

England hospital deaths in detail

Today's highest ever wave 2 number 361 has some big numbers, of course. But this hopefully should be the highest numbers until next week. If it isn't then that may well be a concern.

10 Nov adds 40 = 40 after 1 day (34 was added last week)

9 Nov adds 164 = 203 after 2 days. (122 was added last week). This is the biggest daily add on in 6 months, And the highest day 2 total (and first over 200) since 6 May. Same as Scotland's death data today went back.

8 Nov adds 71 - 213 after 3 days, (52 was added last week). This is also the biggest and first over 200 3 day total since 6 May.

7 Nov adds 42 = 235 after 4 days. (38 was added last week). This is the highest daily total deaths ascribed to any day in wave 2 and the highest since May 7 even after 6 months of add ons to every day since. And the highest day 4 total since 1 May.

6 Nov adds 24 = 209 after 5 days, (18 was added last week) 4 of the last 6 five day totals have been over 200. After none before that since 7 May.

5 Nov adds 4 and = 202 at 6 days and 4 Nov adds 5 and - 228 at 7 days.

The other add ons were onto nine further different dates back to 15 Oct. These are getting too numerous to add and I am sure nobody really needs to know that October 30 now has had 193 deaths instead of 192.

So unless there is something necessary to record I will stick to the first week of numbers from now onward.

When it gets possible to do otherwise it will mean numbers have tumbled and we have turned the corner.

 

[Summerbuzz]

Reasonable article on the subject;

Reuters | Breaking International News & Views

Find latest news from every corner of the globe at Reuters.com, your online source for breaking international news coverage.

uk.reuters.com

Apparently, assuming the vaccine is transported in an ultracold state, and delivered in a standard refrigerator, there is 5 day window in which to administer the doses before they spoil - which can be extended through restocking dry ice and only opening the freezer once a day. How practical this is, I dunno.

 

[03 March 2002]

Bollocks i am afraid , the out of hospitals setting dont have that facility ,gp surgeries and care homes certainly dont and they have to be able to store them because giving the jab is time consuming as they have to be drawn up and double checked before use, it is a huge logistical problem

As far as I understand it this candidate is to be transported at -70c, easily done, and can be stored in the fridge for a max of 5 days thereafter. They won't need to be stored at the place of administration and a roll out plan will mean that the vaccines are divvied out as per requirements.

I'll say again, by the time this hits the market I'll be surprised to see this isn't stored at -20c or better, 2-8c. At the end of the day it's encapsulated in a lipid nanoparticle. I've worked with such therapeutics and actually found they are annoyingly stable. To the point where you have to use 'aggressive' techniques to break down the lipids to get at the damn thing.

 

[Healdplace]

This is what I asked, but it seems our resident itk, is satisfied we don't need to

I posted last night what Matt Hancock said on the storage issues. Regions are being asked to set up by 1 Dec GP surgeries that DO in every region covering up to 3 surgeries - so most patients will likely have to go further afield than their own local surgery.

In the first run though it will be care home patients and staff and over 80s so most of them likely cannot even get to surgeries.

 

[mancity1]

The states have more people in hospital now than at the peak of the first wave so i dont agree with your assumptions

Worldwide Kaz , and we are taking about serious/critical cases as a percentage of total cases.

Don't forget in the states especially in New York they were dying at home in big numbers and that genius of a bureaucrat in New York let covid positive people back into nursing homes.

Even idiotic governments like the one we have in Victoria who are not only inept but corrupt as well as I have well documented and the State Premier should have resigned long ago have got the number down to zero in Melbourne albeit after locking us in our own homes for 4 months.

 

[lancs blue]

Reasonable article on the subject;

Reuters | Breaking International News & Views

Find latest news from every corner of the globe at Reuters.com, your online source for breaking international news coverage.

uk.reuters.com

Apparently, assuming the vaccine is transported in an ultracold state, and delivered in a standard refrigerator, there is 5 day window in which to administer the doses before they spoil - which can be extended through restocking dry ice and only opening the freezer once a day. How practical this is, I dunno.

Thanks for the link, I was about to ask how quickly the vaccine degrades at "normal" fridge temperatures.

 

[Healdplace]

So today's three nation case total (without England) is 2980.

Versus 3740 (3 wks ago) v 3456 (2 wks ago) v 3314 (last wk)

So a steady if unspectacular fall over the month.

Last week's 3314 became 25, 177 when the England cases were added.

 

[mosssideblue]

I posted last night what Matt Hancock said on the storage issues. Regions are being asked to set up by 1 Dec GP surgeries that DO in every region covering up to 3 surgeries - so most patients will likely have to go further afield than their own local surgery.

In the first run though it will be care home patients and staff and over 80s so most of them likely cannot even get to surgeries.

Lost me a little. Are you saying places that will administer the vaccine will have to have dry ice storage conditions?

 

[kaz7]

As far as I understand it this candidate is to be transported at -70c, easily done, and can be stored in the fridge for a max of 5 days thereafter. They won't need to be stored at the place of administration and a roll out plan will mean that the vaccines are divvied out as per requirements.

I'll say again, by the time this hits the market I'll be surprised to see this isn't stored at -20c or better, 2-8c. At the end of the day it's encapsulated in a lipid nanoparticle. I've worked with such therapeutics and actually found they are annoyingly stable. To the point where you have to use 'aggressive' techniques to break down the lipids to get at the damn thing.

How is it going to go from 70c to. 2-8 c ? This is meant to be rolled out in the next few weeks . Not point saying there are not going to be problems in distribution, storage and administration because they are obvious , people will have to be patient