COVID-19 — Coronavirus

[kaz7]

I maybe wrong here, in fact I probably am, but were we not well on the way towards a vaccibe for MERS/SARS? I thought that they were abandoned as both viruses died out and it was not worth the expense in pursuing any longer.

This is a different ball game and it will be financially worth it for any establishment to cone up with a vaccine. I have not seen any person in the know say that it would be impossible to make a vaccine.

You can't get anyone more in the know than him,it has proven difficult to make a vaccine for this group of viruses,they are very clever and change slightly to stay alive,there are lots of potential covid vaccines in trials and we have to see if one can be found,that works,is stable and safe and then mass produced,i think he us just tempering expectations a bit

https://wellcome.ac.uk/what-we-do/our-work/vaccines

There's also the strong possibility that SARS-CoV-2 will continue to mutate.

Being an animal virus, it has already likely mutated as it adapted – first to another animal, and then jumping from an animal to humans.
https://www.sciencealert.com/who-says-a-coronavirus-vaccine-is-18-months-away

 

[kaz7]

Latest I heard from Dr. Birx who's been advising Trump (or trying to) is that getting the virus and recovering from it might not give immunity after all. Lots of hopes have been pinned on this but they just don't know yet. Might have to wait for a vaccine that's coming - in a year or so. Better stock up on supplies again.

Yes the WHO and other people doing trials are not find much immunity

 

[BosnianBlue]

Test and trace is the centre-piece of the USA's exit from lockdown, South Korea etc. It will choke off the virus and is doing in those countries which are executing it, however, I think the UK is reluctant to do it too soon. I think they would like to keep the infection rate relatively high so that immunity is acquired but at the same time they want to prevent the hospitals from being overwhelmed. Once we've got a significant amount on infection in society I think they want to keep the infection ticking a long at a steady rate. That way we are closer to acquiring immunity. I don't agree with this approach but I think it is what they are up to because it explains everything we see them doing, or not doing.

Did you see that the Swedish epidemiologist is claiming that Stockholm maybe close to acquiring immunity? I don't believe that. They have still been social distancing but just not as strongly as other countries.

They are basically in quarantine, it's just ont obligatory one. The journeys from Stockholm to Gotland, traditional one during Easter fell 96% this year and mobile phone companies anounced that general movement inside Stockholm is 75% down. They haven't closed schools and you'll see some people in restaurants and bars, but these data show they are basically self-quaranting in masses. They are pretty specific country anyway, almost half of the country lives in one member households.

 

[denislawsbackheel]

I maybe wrong here, in fact I probably am, but were we not well on the way towards a vaccibe for MERS/SARS? I thought that they were abandoned as both viruses died out and it was not worth the expense in pursuing any longer.

This is a different ball game and it will be financially worth it for any establishment to cone up with a vaccine. I have not seen any person in the know say that it would be impossible to make a vaccine.

There is no vaccine for any corona virus.
Couldn’t be clearer could it?

 

[SWP's back]

Virginia Gov. Ralph Northam called out President Trump for claiming that the U.S. had the testing capacity to begin reopening portions of the economy, saying that his state has been dealing with shortages ever since the virus first emerged in the state:“That’s just delusional to be making statements like that.”

https://thehill.com/homenews/state-...s-its-delusional-for-trump-to-say-states-have

 

[SWP's back]

There is no vaccine for any corona virus.
Couldn’t be clearer could it?

There’s never been a need. They were nearly there with SARS but as the poster you quoted said, the virus dropped off and was funding was pulled.

Or are you saying it’s impossible? (Despite the 70+ different vaccine trials being underway?)

 

[denislawsbackheel]

No, I am saying there never has been a vaccine for any human corona virus.
Nobody knows whether a SARS vaccine would have been viable. One was never produced.
So a little caution ought be advised in people who think there will be one.

 

[BosnianBlue]

No, I am saying there never has been a vaccine for any human corona virus.
Nobody knows whether a SARS vaccine would have been viable. One was never produced.
So a little caution ought be advised in people who think there will be one.

it's definitely not guaranteed, but sars and mers ones were pretty advanced and since they are almost identical to covid, the experiences were precious and will help this one to develop much faster. I'm pretty confident they'll make it, it's only the timestamp I'm worried about. even the most optimistic one is 5-10 times shorter than usual vaccine development. Regular vaccine development goes as far as 10-15 years to hit the public.

 

[kaz7]

There’s never been a need. They were nearly there with SARS but as the poster you quoted said, the virus dropped off and was funding was pulled.

Or are you saying it’s impossible? (Despite the 70+ different vaccine trials being underway?)

Most drugs tested don't make it to market for one reason or another,there is a long way between having something work in theory or animals and treating patients with it

 

[blueish swede]

Interesting....

Sweden claiming may have herd immunity by next month....

https://www.dailymail.co.uk/news/ar...y-month-claims-infectious-diseases-chief.html

Test and trace is the centre-piece of the USA's exit from lockdown, South Korea etc. It will choke off the virus and is doing in those countries which are executing it, however, I think the UK is reluctant to do it too soon. I think they would like to keep the infection rate relatively high so that immunity is acquired but at the same time they want to prevent the hospitals from being overwhelmed. Once we've got a significant amount on infection in society I think they want to keep the infection ticking a long at a steady rate. That way we are closer to acquiring immunity. I don't agree with this approach but I think it is what they are up to because it explains everything we see them doing, or not doing.

Did you see that the Swedish epidemiologist is claiming that Stockholm maybe close to acquiring immunity? I don't believe that. They have still been social distancing but just not as strongly as other countries.

2 separate studies have come to similar conclusions: about 1/3 of Stockholm have or have had the virus. A population of about 2,35 million and there have been 5826 recorded cases. Thats abou 1 in 400 showing significant symptoms.

 

[SWP's back]

Most drugs tested don't make it to market for one reason or another,there is a long way between having something work in theory or animals and treating patients with it

Good job there’s more than 70 of them being tested then isn’t it.

 

[SWP's back]

2 separate studies have come to similar conclusions: about 1/3 of Stockholm have or have had the virus. A population of about 2,35 million and there have been 5826 recorded cases. Thats abou 1 in 400 showing significant symptoms.

Can’t find anything in English after a quick google search for the emboldened part.

 

[kaz7]

Good job there’s more than 70 of them being tested then isn’t it.

Only 5 in 5,000 drugs that enter preclinical testing progress to human testing. One of these 5 drugs that are tested in people is approved. The chance for a new drug to actually make it to market is thus only 1 in 5,000. Not very good odds.

https://www.medicinenet.com/script/main/art.asp?articlekey=9877

I think we will get one as the whole world is working on it,i think the guy from Wellcome trust is just being cautious

 

[SWP's back]

Only 5 in 5,000 drugs that enter preclinical testing progress to human testing. One of these 5 drugs that are tested in people is approved. The chance for a new drug to actually make it to market is thus only 1 in 5,000. Not very good odds.

https://www.medicinenet.com/script/main/art.asp?articlekey=9877

I think we will get one as the whole world is working on it,i think the guy from Wellcome trust is just being cautious

Yeah and there are more than five already with human trials which is great. (Vaccines are also slightly less complex than other drugs as they’re essentially denatured pathogens, so we have a good starting point).

Humankind is rather amazing when given great motivation and limitless funding.

 

[blueish swede]

Can’t find anything in English after a quick google search for the emboldened part.

I heard Anders Tegnell (epidemiologist) on the readio. Hes with the Health Ministry and they did one study. The other is from a mathematical model by prof. Tom Britton at Stockholms University. I'll keep looking for links in English.

 

[twosips]

Yeah and there are more than five already with human trials which is great. (Vaccines are also slightly less complex than other drugs as they’re essentially denatured pathogens, so we have a good starting point).

Humankind is rather amazing when given great motivation and limitless funding.

Anywhere I can read up about the 5 already in human trials?

 

[Nightmare Walking]

There is no vaccine for any corona virus.
Couldn’t be clearer could it?

I understand that mate, but I was asking whether the fact we currently have no vaccine is because of theoretical and practical implications of making them or is it purely financial?

I was watching something the other night and the experts were suggesting the only reason we do not have a vaccine for coronaviruses is because of financial implications. In regards to the common cold, because it is harmless in the grand scheme of things and there is a whole industry surrounding common cold relief, it is not worth anyone making a vaccine. In regards to SARS/MERS, they said there was good progress made in regards to a vaccine but then they were mothballed due to them dying out. From a theoretical perspective they said there was nothing inhibiting a vaccine being developed.

Now it is difficult to know what or who to believe. There are just so many conflicting stories. Now we are hearing there may be no immunity, no antibodies, no vaccine, if you get put on a ventilator then you are pretty much done for anyway. I am going to try and remain a bit more positive than that. I remember the absolute horror stories the media and medical professions were coming out with regarding HIV. 30 years on there are now treatments and it is no longer a death sentence. No one knows how this particular episode will turn out. It seems like we are playing for time and that is the way to go about it. It is impossible to expect the authorities to have everything under control and a cure/vaccine in less than 6 months. We all need to adhere to the social distancing rules, try to limit the spread and give the scientists and medical professions the time needed while educate themselves and gain more understanding of the virus, before trying to come up with a feasible plan to mitigate the effects of the virus.

Everything seems to be best guess at the minute. I spent longer doing my dissertation at uni than people have had to try and work out a solution for this global pandemic. I am going to take all the necessary precautions to keep myself and my loved ones safe. But I am going to take all these claims about what may and may not be with a pinch of salt, until the authorities have a better understanding of what is going on and the best course of action.

 

[SWP's back]

Anywhere I can read up about the 5 already in human trials?

1) Washington State

2) Australia

3 & 4) China

5) United Kingdom

There’s five for you. I believe there may be many more.

 

[SWP's back]

I understand that mate, but I was asking whether the fact we currently have no vaccine is because of theoretical and practical implications of making them or is it purely financial?

I was watching something the other night and the experts were suggesting the only reason we do not have a vaccine for coronaviruses is because of financial implications. In regards to the common cold, because it is harmless in the grand scheme of things and there is a whole industry surrounding common cold relief, it is not worth anyone making a vaccine. In regards to SARS/MERS, they said there was good progress made in regards to a vaccine but then they were mothballed due to them dying out. From a theoretical perspective they said there was nothing inhibiting a vaccine being developed.

Now it is difficult to know what or who to believe. There are just so many conflicting stories. Now we are hearing there may be no immunity, no antibodies, no vaccine, if you get put on a ventilator then you are pretty much done for anyway. I am going to try and remain a bit more positive than that. I remember the absolute horror stories the media and medical professions were coming out with regarding HIV. 30 years on there are now treatments and it is no longer a death sentence. No one knows how this particular episode will turn out. It seems like we are playing for time and that is the way to go about it. It is impossible to expect the authorities to have everything under control and a cure/vaccine in less than 6 months. We all need to adhere to the social distancing rules, try to limit the spread and give the scientists and medical professions the time needed while educate themselves and gain more understanding of the virus, before trying to come up with a feasible plan to mitigate the effects of the virus.

Everything seems to be best guess at the minute. I spent longer doing my dissertation at uni than people have had to try and work out a solution for this global pandemic. I am going to take all the necessary precautions to keep myself and my loved ones safe. But I am going to take all these claims about what may and may not be with a pinch of salt, until the authorities have a better understanding of what is going on and the best course of action.

This is a good article that gives me some cause for optimism. So I keep reposting it.

https://www.city-journal.org/coronavirus-vaccine

 

[Nightmare Walking]

This is a good article that gives me some cause for optimism. So I keep reposting it.

https://www.city-journal.org/coronavirus-vaccine

I shall give it a read mate, cheers.

I am an eternal optimist anyway, no chance I am letting this get my down.