Many thanks for the replies re 1 Piccadilly. And would definitely agree that although the city centre looks better than it has for a while, much of the character of the old brick and stone type buildings seems to be going (not that I've been into central Manchester in years, so only going by appearances. It's a pity that not even one of the new buildings seems to have scored a stir as a design; where's the equivalent of the gherkin or the shard?
Now that I've taken the thread off topic I might as well keep going and the mods can hang me for a sheep instead of a lamb. In Bill Bryson's book about travelling around Britain ('Notes from a small island'?) he says about Manchester something along the lines of it has no clear centre, no heart. Basically, nowhere that is Manchester in one image. As soon as I read it I knew he was right and that I'd probably known that myself for a long time. Piccadilly gardens was probably as good as it got, but it wasn't anything much. The square in front of the town hall is probably it now, but neither of those came be called iconic.
Does anybody disagree? Are Bill and myself out of date and things have changed? Would a nice big plaza somewhere (maybe with something in it/around it) be a paradigm shift?