Including MD in the list is pointless.
It would be Mangala all day for me, he's a work in progress (yes I know he's 25) but three years younger than Otamendi who only really 'clicked' as a consistently good player at the same age, he's been our best defender over the last couple of months, usually been really consistent when actually given a run of games, he's got a decent attitude and some character and appears to actually give a fuck.
Vinny is worthy of another year to see if he can recover himself physically imo, however if we're being ruthless it really doesn't look good when different parts of the body keep breaking down so regularly.