Yes. Apart from the countrywide reach they have the unnatural grouping of the former Mirror Group papers with Express Newpapers which take opposite political views but altogether they can influence their hard of thinking readers without them even realising it.
But it is football where their combined might affects us as they are so heavily biased towards the Redshirts. Worst still, both the Mail (Samuel excepted) and the Sun get into the same bed. As a result the country as a whole does not have a satisfactory coverage of the game it exports to the world.