Almost all neutrals (myself included) are hoping the Cubs somehow do it this year. They haven't won a World Series since 1908 and their fans deserve it. If they don't they won't be too upset because it does look like they'll probably be strong for a number of years though due to their youth. They were supposed to be a year away from serious contention but things are falling into place early.
In the AL I really hope Kansas City get there again. I can't stand the Blue Jays and their jackass right fielder Jose Bautista. They wouldn't even be here if it weren't for the epic collapse of the Rangers' defense in the ALDS.