Pretty much everyone will lose at Stamford Bridge, they've won 12 of their 13 home games in the league so far, the one draw being 3-3 against Everton. This is one of those games where any sensible City fan predicted a defeat pre-season, and their predictions shouldn't have changed. What this means is we should be able to relax into the game and play with a greater degree of freedom, the pressure is off, no-one expects anything other than defeat. Whether Mancini allows City to do this or not is debatable (I'd go with him enforcing the turgid defensive displays of recent games if I werer a betting man).
I can't see anything other than a comfortable Chelsea victory, 2-0 to Chelsea for me. Any kind of positive result will be a huge boost and additional points no-one should have factored into our end of season total.