This is another tough one to pick.
Aguero and Sterling both played 120 minutes, Jesus 82 min and Sane played 25 minutes.
Wouldn't mind seeing a 3-5-2 again.
--------------------------------------Ederson-----------------------
---------------------Otamendi----Stones---Danilo-----------------------
----Walker---De bruyne-----Fernandinho----D.Silva--------Delph-------
-------------------------------Jesus-------Sane-----------------------------------
Other wise 433 and Sterling for Danilo but starting Sterling or especially Aguero is a major risk IMO, we risk fatigue and injury.
I think a 352 would be good because our freshest players would play, we can bring on Aguero for Jesus early in the second half and after that Sterling for Sane. Then either Gundogan or Bernardo for David or Kevin.
For Napoli I would start Sterling, Jesus, Sane because we need Jesus over Aguero for his pressing which will be crucial against Napoli. Aguero can be fresh to start against Arsenal.
A big 3 games coming up and managing fitness will be key IMO.