Coronavirus (2021) thread

[ganganvince]

Why the need to check into venues?

Extra security but most get zapped from normal contact

 

[ctwrd]

Wimbledon’s 50% capacity a bit of a joke. You’d think spaced apart. No just top half of centre court is completely empty everyone squashed into front few rows.
Yet again, why is this allowed but it’s murder if you dare think about having more than 6 in your house.

 

[BlueHammer85]

Wimbledon’s 50% capacity a bit of a joke. You’d think spaced apart. No just top half of centre court is completely empty everyone squashed into front few rows.
Yet again, why is this allowed but it’s murder if you dare think about having more than 6 in your house.

have more than 6 in your house at the weekend. you won’t get reported. The police won’t do anything. No one cares.

 

[kevin horlocks wand]

Wimbledon’s 50% capacity a bit of a joke. You’d think spaced apart. No just top half of centre court is completely empty everyone squashed into front few rows.
Yet again, why is this allowed but it’s murder if you dare think about having more than 6 in your house.

they are posh though so it’s fine .

 

[BlueHammer85]

they are posh though so it’s fine .

45,000 at the footie tomorrow

 

[ctwrd]

45,000 at the footie tomorrow

How many actual fans?

 

[Healdplace]

On 18 May Bolton peaked at a Pop Score of 458 as posted above. It has slowly fallen to 286 today - though a week ago it was down on 239 and has been rising slowly again since.

Manchester today has gone above that highest Bolton number. Onto 480. On 18 May it was just 59. It has gone up relentlessly every day since.

On that day - 18 May - here are where the other GM boroughs were at that point and what they have done since.

Bury was 53 - has gone up without stopping to 375

Oldham was 28 - has gone up without stoppin to 359

Rochdale was 40 - has gone up steadily to 353

Salford was 31 - has risen inexorably witrh a brief pause around 330 10 days ago to now be close to top on 462/

Stockport was 14 - rose more slowly to 228 then fell for two weeks to 194 about 9 dys agp and edged up to 257

Tameside was 18 - stayed below 100 for 2 weeks then went up and up to 332

Trafford was 46 - slowed a little two weeks ago but has gone upsteailysince to 338

Wigan was 26 and has just gone up and up ever since accelerating in past two weeks going from 235 to 438 in 15 days,

 

[Tim of the Oak]

She’s never checked in anywhere with it

You don’t need to check in. She will have been in close proximity to somebody with the virus for the required length of time.

 

[BlueAnorak]

AZ study shows that a third dose given 6 months on from second one does boost protection further.

Boosts protection against all current variants including Delta.

But Oxford study adds it is not clear immunity wanes enough after 6 months that a third dose this winter is needed. And that it would be morally wrong to prioritise that over AZ being gven to vaccinate the parts of the world still needing first and second doses and so in more need than the UK.

Caveat - small numbers of people in the test almost self evidently. As we only started vaccinating anywhere 6 months ago so real world data on this is still some way from being clear outside the early tests.

And if its the other vaccine AZ instead of Pfizer (or vice-versa) it will be even better still.

Mix-and-match COVID vaccines trigger potent immune response

Preliminary results from a trial of more than 600 people are the first to show the benefits of combining different vaccines.

www.nature.com

 

[BlueAnorak]

ENGLAND HOSPITAL DEATHS SUNDAY

The single death was from 25 June and in Birmingham. They were aged 80 +


ENGLAND HOSPITAL DEATHS MONDAY

The two deaths today were both in the North West, one on Friday and the other on Saturday.

One was aged 40 - 59, the other ages 60 - 79.

One was in Manchester Royal and the other in Salford Royal.



Although the really big numbers were on Saturday and the two following days were encouraging - so overall not a really worrying total - it is hard to be sure as weekend registering of deaths is always low especially in the North West,

As we stand that new high of 12 on 24 June is still at 12 after another 2 days. But being weekend days we will have to see what its 5 day total is tomorrow when numbers will be more normal than Mondays are.

Similarly the 5 we started out with on 25 June are still only at 7 after 3 days and the same caveat here.

I think these numbers are obviously slowly rising and are, of course, from weeks ago when they likely caught Covid in the EARLY days of the rise then only in the North West.

The regional distribution of the deaths versus the cases show these deaths are not from people who caught it in the last week or two.

It remains to be seen how high the numbers will go as we see the impact of the now double numbers in the NW AND the rising numbers in all other regions.

We are a few weeks away from seeing the degree of that consequence only that it will be a bigger number than now.

I think it is safe to predict the vaccines will assure it is not hundreds of daily deaths at the peak of this wave.

But right now I am not sure it will stay under three figures at its peak.

Let us hope so as this will factor in to how many people will be in hospital to trigger these deaths and taking up icu beds and that is really the scenario we need to stay as low as possible in order to safely open up.

Still optimistic. But it is not assured how high we will go. Just that in coming weeks we will go higher even given how much the vaccines are undeniably helping in a big way.

This virus will always find victims sadly.

I'm absolutely sure deaths won't get anywhere near 3 figures.

 

[ayrshire_blue]

When someone you would usually associate with leaning to a more optimistic outlook changes their tone somewhat, it doesn't sound great.

 

[BlueAnorak]

I think there's more to these vaccine figures than supply issues.

Vaccine hesitancy from those who are living pretty much a normal life right now and either are blaize about getting vaccinated asap or don't understand the need for it so aren't in any hurry would be my guess.

Maybe vaccine passports/certificates would change things.

That Tweet is rubbish

 

[ayrshire_blue]

That Tweet is rubbish

In what way?

 

[BlueHammer85]

I'm absolutely sure deaths won't get anywhere near 3 figures.

I’m not when we’re hitting 18+ thousand infections - remember it takes 3/4 weeks to result in deaths.

but the vaccine is working wonders for sure.

 

[everythingchangesbutblue]

I know someone who as the test and trace app but has never used it, yesterday it’s informed her that she needs to self isolate.
Looking like quotas are needed to be met

So you are saying there is a conspiracy?

 

[Summerbuzz]

So you are saying there is a conspiracy?

No, he's detailing it. Secret quotas.

Could just be his mate forgot he used it, doesn't know how to use their phone, or is a liar.

Or it could be SECRET QUOTAS designed to... umm.. how would that work? Oh yeah. Gotta keep the population in fear.

There's no fooling our Keith. Recognises a made up scare story when he sees one. Probably because he spouts them all the time.

 

[Manc in London]

Consultation launched on closing face-to-face customer services

Bosses in Tameside are consulting on whether to close their drop in face-to-face customer services for good at the new multi-million pound council HQ.

www.questmedianetwork.co.uk

This is the sort of thing that worries me post Covid. Whether some public services will never go back to 'normal'

Authorities across the country have been doing this for a while. I cannot remember the exact figures but a senior finance manager told me that if someone visits a council access point with council tax query, it costs the council, on average, about £15. Yet for almost all queries, the answers can be found on the council website.

The pandemic is certainly enabling authorities to be bolder with such changes.

 

[Marvin]

Probably been posted already but in case not..

Keep an eye out for progress of the epidemic in UK, SA, Brazil and Poland. Presumably all we need is an efficacy signal?

Trial to enrol approximately 2,250 adults to assess safety and immunogenicity of AZD2816 against the SARS-CoV-2 virus​

​

The first participants in a Phase II/III trial for the new COVID-19 variant vaccine AZD2816 were vaccinated today to assess its safety and immunogenicity in both previously vaccinated and unvaccinated adults.
The trial will recruit approximately 2,250 participants across UK, South Africa, Brazil and Poland.
AZD2816 will be administered to individuals who have previously been fully vaccinated with two doses of Vaxzevria or an mRNA vaccine, at least three months after their last injection. In non-vaccinated individuals, AZD2816 will be given as two doses, four or twelve weeks apart, or given as a second dose following a first dose of Vaxzevria four weeks apart.
AZD2816 has been designed using the same adenoviral vector platform as Vaxzevria, with minor genetic alterations to the spike protein based on the Beta (B.1.351, South African) variant.
Sir Mene Pangalos, Executive Vice President, BioPharmaceuticals R&D, said: “It is important we continue to stay ahead of genetically distinct variants of the coronavirus. AZD2816 should help broaden individuals immune response against emerging variants of concern. Initiating the Phase II/III trial for AZD2816 means we can be prepared should a variant vaccine be required in the future.”
Professor Sir Andrew J Pollard, chief investigator and director of the Oxford Vaccine Group at the University of Oxford, said: “Testing booster doses of existing vaccines and new variant vaccines is important to ensure we are best prepared to stay ahead of the coronavirus pandemic, should their use be needed.”
Initial data from the trial is expected later this year and, once available, will be submitted to regulators for assessment as a next-generation booster vaccine and through an expedited regulatory pathway.
D7220C00001
D7220C00001 is a Phase II/III partially double-blinded, randomised, multinational, active-controlled trial in both previously vaccinated and unvaccinated adults to determine the safety and immunogenicity of AZD2816, a vaccine for the prevention of COVID-19 caused by variant strains of the SARS-CoV-2 virus.
Trial participants aged 18 years or over who are SARS-CoV-2 nucleocapsid seronegative will be randomised to minimise group differences in terms of age, gender and the presence of comorbidities. Participants will receive intramuscular administration of either Vaxzevria (5 ×1010 viral particles) or AZD2816 (5 ×1010 viral particles). In addition, seropositive participants will be enrolled, with a cap of 10% of the seronegative population, to support exploratory analysis.
AZD2816
AZD2816 has been built using the same adenoviral vector platform as with Vaxzevria, with minor genetic alterations to the spike protein based on the Beta (B.1.351, South African) variant. The Beta variant vaccine contains ten changes across the spike protein, many of which are also seen in other variants of concern, and which lead to effects such as, reduced ability of antibodies induced against the original virus to block cell entry (K417N, E484K, N501Y); increased infectivity compared to the original virus (D614G); reduced sensitivity of neutralising antibodies to the original virus (L452R). These modifications are only minor and in all other ways the two vaccines are the same.

 

[BlueAnorak]

I think most people expected it to at least blunt the growth by now.

Well the outbreak is showing down in areas of high vaccination - even in lower vaccination areas iwhere Delta first got a hold it is, so herd immunity probably is kicking in now.

 

[Tim of the Oak]

Well the outbreak is showing down in areas of high vaccination - even in lower vaccination areas iwhere Delta first got a hold it is, so herd immunity probably is kicking in now.

Some of these communities saw the epidemic in India and took Covid more seriously