Coronavirus (2021) thread

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Firstly, the conclusions being drawn from this study is that the 502.V2 variant would render these vaccines ineffective. This is highly unlikely. It will take a large amount of genetic diversity to completely render the current vaccines useless. Why? Vaccines are polyclonal.

This study didn’t even look at the vaccines. They studied OLD blood sera from NATURAL infection. Therefore they already contained low antibody levels. Why is this an issue? Because everyone knows antibodies from natural infection with COVID are weak and wane in 2-3 months.


Please take note of where the study says that over half of the samples did neutralize due to the fact they had a more robust immune response. Hello? This is what vaccines do? Antibody counts would be sent high? Not to mention the study TOTALLY disregarded B-cells and T-cells.

How are you going to disregard our actual immune systems and their ability to make antibodies for later? Which may I remind you are DRIVEN by vaccines. They teach our bodies to make antibodies for later, not just during active infection (memory T-cells anyone). That’s immunity!

T-cells stimulate B-cells to make antibodies. Antibodies are just your first line of defense which is what is initiated when you get this vaccine. It’s our T-cells that are responsible for long-term immunity. When antibodies diminish after your initial inoculation, your T-cells-will tell your B-cells it’s time to produce more antibodies. As long as your T-cells still recognize this virus and inform your B-cells they need to produce antibodies, the vaccine is still doing its job. Antibodies being built up over and over again is nothing new or unique to this vaccine, this is how vaccines have always worked. This study does not account for this information concerning T-cell immunity AT ALL.
I really enjoyed reading this thoughtful and detailed post, cheers.
 
One thing I see is people hoping cases will come down sharply as we vaccinate but they should bear in mind these are not correlated much.

Even though hundreds of over 80s die from this daily and so rightly are prioritised for the vaccine for that reason they are actually at low likelihood of catching it because most are shielding.

The numbers testing positive over 80 daily is in single figure percentages in most places. By far the majority who are testing positive daily are in the 15 to mid 60s age range.

The lowest numbers are in the 65 - 90 age range as they are likely being far more careful and, of course, tend not to be in as many day to day work situations that put them into contact with others.

So there are few vaccinations (apart from key workers like the NHS which will have an impact) in age groups that are catching this the most.

Hence why we are watching the percentage of age groups in deaths for the first hints the vaccines are working as they are going to decrease infections too but from an already very low level. So case numbers are not going to be dramatically impacted right now by vaccinations. As most catching it are weeks or months away from being vaccinated.
 
One thing I took from the press conference was the news that Asian and Black communities are the concern group for declining the vaccination offer. The doctor didn’t give stats so not sure how bad that is but clearly a concern.
It’s on North West Tonight now. A Youth Worker from Moss Side is saying he’s had a lot of youth and young adult black people coming to him with conspiracy theories about Covid.

In a recent survey:
72% of black people say they won’t have the vaccine.
Compared to 42% of Asian and 15% of white people.

The youth worker said there needs to be some black doctors and role models coming forward to promote the vaccine to black people.

It’s alarming though! Where are these 72% 42% and 15% spending their time? Where are they getting their information? What are they reading? Who’s influencing them?
 
Whilst checking this on Gov UK by the way I looked at the heat map pictures of Oldham.

The outbreaks in March/April and October/November that drove Oldham up and away is visually very quickly apparent as different from the one happening now.

You can see a big gap that is in the January outbreak painted in colours on this map by the numbers testing positive in Oldham. That gap is in the older ages.

There are some small dark blackish purple blobs indicating high levels but far less than in past outbreaks and most of the area is blue and around the level of the under 15s. By far the bulk of the outbreak is in the middle age groups and even these are less intense colours so less numerous.

I suspect partly this is because they only tested the sickest last April and they tended to be the oldest. And the current wave is likely nowhere near the level of the past two and is just down across the board.

But the demographics do appear to have changed somewhat. Probably because the younger are more frustrated ad willing to break curfew than the older who will know they have most to risk by doing so in a way they would not at the start.
 
It’s on North West Tonight now. A Youth Worker from Moss Side is saying he’s had a lot of youth and young adult black people coming to him with conspiracy theories about Covid.

In a recent survey:
72% of black people say they won’t have the vaccine.
Compared to 42% of Asian and 15% of white people.

The youth worker said there needs to be some black doctors and role models coming forward to promote the vaccine to black people.

It’s alarming though! Where are these 72% 42% and 15% spending their time? Where are they getting their information? What are they reading? Who’s influencing them?
Facebook and twitter probably it's full of conspiracy theorist fuckwits
 
That 1290 all settings is a significant fall in the number on Tuesday when the numbers were the same from everywhere else (England hospitals and the other 3 nations all settings - so only without England out of hospital deaths added in.)

So there was a very large add on of out of hospital deaths on Tuesday and Wednesday.

Today it is only 345 versus 635 England out of hospital added on yesterday and 665 added on Tuesday.

There is always some weekend catch up but that looked extreme. And still does.

Possibly there was a lot of post Christmas/New Year catch up as out of hospital deaths may take longer to verify than those in hospital. A delay of a week or two is not hard to imagine.
When I see that hospitals like Kings Lynn (38 deaths) or Frimley (36) report numbers MUCH higher than average I assume that some NHS Trusts only submit info. up the line in batches.
 
Few mentions of Glasto in here today.

Whilst it's a bit of a blow to the festival/events/entertainment industry to see it cancelled, it was pretty much inevitable.

It's one of the earlier festivals in the summer calendar, and by all accounts its a 6 month logistical operation to get it all ready. Which basically means they had to decide this month whether to go for it or not. I imagine it would've been a financial disaster to crack on in the unlikely event it could happen, to only then have to call it off in April/May.

Some of the smaller festivals might have a chance of going ahead, though time will tell.

Really feel for everyone connected to the live music industry, them and travel have been absolutely battered and there is no end in sight.

Cannot wait to go to a gig again when the time is right.
 
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