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Summerbuzz
Guest
I came of 45mg but I still take Venlafaxine. I know others who are in the same boat, off Mirtazipine but still on something else.I forgot to take my minimum dose mirtazapine tablet the other night. Fuck me, Not only could I not get off to sleep for hours, I fell into a really black mood and lay there working out ways to top myself.
It is terrifying to think that such a tiny tablet makes such a difference. I am back in my proper senses now, but I wonder if I will ever get off this pill.
The sleeplessness would resolve itself in a few days. Your body is just used to the particular effect of the drug that knocks you out. It hits the H1 receptor in the brain that governs wake/sleep cycle. It's the same mechanism as antihistamines like diphenhydramine / Benadryl.
But there's a psychological thing as well, we have to little things we do routinely as signalling bed time to trick us into falling asleep. Also worth noting that if you are taking the pil that dissolves on your tongue, this is very fast acting.
As for your ability to cope without the antidepressant effect, that might be different. Mirtazipine gave me a sort of sheen over my senses that made it easy to live with things, was easier to take pleasure. I still sort of miss it, but I've coped with COVID and tragedies and many other things without it, and am going through one of my best periods in years. I hope things work out well for you.
Advice is therefore kind of: I wouldn't worry that much. It would get easier if you did. As long as it was the right time for you, your body would adapt quickly enough.