Manchester City v Wolverhampton Wanderers
Manchester City made 11 changes when these two sides met in the Carling Cup in midweek, so their boss Roberto Mancini is clearly going to reload the side that thrashed United last weekend when they meet again on Saturday - which is unlucky for Wolves manager Mick McCarthy.
I am totally on McCarthy's side in terms of his reaction to the treatment he got from fans in last week's draw with Swansea, when they chanted 'you don't know what you're doing' at him after he made changes of personnel and tactics.
He got himself out a hole by pulling that game from 0-2 to 2-2 and is very much still the man for the job at Molineux, but I cannot see him getting anything from this trip to the Etihad Stadium.
City's win at Old Trafford will have reverberated around Europe, not just the Premier League, but the only thing I would say about the 6-1 scoreline is that it was only 1-0 when United had Jonny Evans sent off and those three late goals which gave it such a resounding look were because United were still trying to get something from the game with 10 minutes left.
It is a sea-change result, no doubt about it. But just because they have won at Old Trafford and scored six goals, City have not won the league.
They are clear at the top, which is a new situation for them, so forget about the euphoria for a while because for now they just need to keep winning. I think they will beat Wolves but I think it will be much tighter than their 5-2 win in the Carling Cup.
Prediction: Manchester City 3-1 Wolverhampton Wanderers