Manchester City are without Fernandinho and Aymeric Laporte, both of whom suffered muscle injuries in Sunday's Carabao Cup final win.
John Stones and Gabriel Jesus remain sidelined, while Benjamin Mendy is nearing fitness and will be assessed.
West Ham manager Manuel Pellegrini has reported no new injury concerns.
Manuel Lanzini is again likely to feature as a substitute, having made his comeback from a long-term knee problem in Friday's win against Fulham.
Defenders Fabian Balbuena and Winston Reid have returned to light training but are not yet fully fit.