Coronavirus (2021) thread

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It sounds like the variants work better because they have an increased affinity for the ACE2 receptor. If their affinity has changed for the receptor it follows that the antibody binding affinity may also change. I am guessing so people shouldn't worry if they read my comments.

Broadly, you're correct - any mutation may change the spike protein enough to make a vaccine not 'cap' it well.

It's guesswork for you and me without the pharma companies' big modelling computer power. There are thousands of things that can mutate in the RNA, some have no effect.
 
So what's the difference between lockdown and tier 4, apart from schools closing?
Shops only selling food and medicine
Schools colleges and universities to close
No bubbles for people living alone
No outdoor leisure group settings (my Nephew’s football training is still going ahead, he’s not going though)
No indoor leisure 1-1 settings (my Niece is still able to do 1-1 swimming lessons, she’s not going though)
Only one exercise session outdoors per day
No weddings
No funerals
Vulnerable shielding
Police presence on the streets
... and probably more

Borders closing?

Tier 4 isn’t particularly strict. You’d imagine that a full lockdown would actually be about Tier 6.
 
Shops only selling food and medicine
Schools colleges and universities to close
No bubbles for people living alone
No outdoor leisure group settings (my Nephew’s football training is still going ahead, he’s not going though)
No indoor leisure 1-1 settings (my Niece is still able to do 1-1 swimming lessons, she’s not going though)
Only one exercise session outdoors per day
No weddings
No funerals
Vulnerable shielding
Police presence on the streets
... and probably more

Borders closing?

Tier 4 isn’t particularly strict. You’d imagine that a full lockdown would actually be about Tier 6.
I think no funerals might be a bit harsh!
 
the borders are open, fly where the fuck you like where you want to and anyone and everyone in the world can come and go as they please
Without wanting to get into an argument here, have you seen the amount of air traffic there is in the UK (and Europe) just now, it's virtually nil, and who knows how many people are on these planes ?

Under current tier 4, the rules say "People should not leave tier four areas or travel abroad, except for limited reasons (including work and education)", so work travel is allowed, and I've said it before in this (or the old) thread that there are thousand who work in the oil, gas, and chemical industries who do have to travel for work.
 
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