Coronavirus (2021) thread

[Indaparkside]

I'm becoming more worried about the government than the virus.

You’ve only just realised this

 

[Marvin]

Its weird the countries that have handled it badly, UK, SA, Brazil all seeing significant variants but the Swedes haven't even though they now admit they got things wrong. I'm sure at one point they were on the travel corridor list too.

Numbers game. It's very interesting that the mutation that has occurred in South Africa that enables it to escape an antibody reaction has occurred independently in the UK. We are seeing the same mutation in different strains across the world. What this tells you is that there are certain structures which are stable and confer an advantage and will repeatedly occur across the world wherever there is a lot of virus. We could stop all travel to South Africa, and we'd still end up with strains carrying similar mutations to the SA variant. We are seeing that happen. If we are really smart we will work out what the next mutations are going to be before they even happen. We know what the human receptor cell looks like on the molecular level. We know that the spike protein looks like. The changes that are effective are those that produce a stronger binding affinity between the two molecules. Swap amino acid residues, add extra ones, delete others. You can probably do it with a computer program.

Molecular simulations are done all the time where you take a sequence of amino acids and put in in a solvent and then watch it fold. It's called Molecular Dynamics simulations. You apply forcefields such as the Lennard Jones Potential and then run Monte Carlo simulations which move the molecule picometers and sum up all the different interactions step by step so that you can model how the molecule will form. You can make your model in a computer and then check it with X-ray diffraction.

 

[Gray]

The NHS booking site is not working this morning. Typical - they ask all over 70's to book a vaccination if they have not already done so, then when you try you can't.

Who is in charge of these web sites?

 

[paulchapo]

You’ve only just realised this

No I haven't but anyone raising these concerns gets slaughtered here.

 

[Gray]

JVT doing a Q &A on BBC 2 right now.
Can't say I was aware of this one.

Can somebody ask him why the vaccination booking site is not working?

 

[hammocity]

I'm becoming more worried about the government than the virus. This is never going to end I'm afraid, that is becoming clearer by the day.

Just like AIDS, the scientists and medical community will eventually, through hard work, knowledge, a degree of serendipity and experience treat and contain the virus to make it something we can live with without affecting everyday life. I wouldn't be too pessimistic and I'm hopeful this will be the last really challenging year in the fight against Covid.

 

[Indaparkside]

No I haven't but anyone raising these concerns gets slaughtered here.

Agree pal but I’ll say it , this government has been a total shambles from the start, some posters on here would lick their arse if it was covered in shit, they have had a whole year to sort stuff out and badly fucked up fact

 

[Citizen of Legoland]

No I haven't but anyone raising these concerns gets slaughtered here.

There's a political thread in the sub-forum separately where it will be tolerated.

 

[Blue Maverick]

Of course you don't because your problem is, you don't see all the additional costs associated in running a Covid Hotel.

So they walk in stay in their room for 10 days and it’s cleaned when they leave are you telling me it costs over £1000 per person to do this? Maybe i should apply for a job as a cleaner then.

 

[Blue Maverick]

I assume his point is that if it is cheap enough, it will encourage more people to do it. By making the price so high, it should hopefully discourage people. I might be wrong though.

I would think the 10 days would be more of put off mate, cantbsee why anyone wants to holiday here at the moment and if it’s business people then zoom would be better