Dzeko & Negredo are doing ok when they play together.
They are not hitting it off perfectly but they are looking to pass to each other & sometimes linking up for goals which they create for themselves. That is a clear sign that it can work. When a strike partnership creates the goal for themselves.
For a brand new pairing who haven't started many games together, it's not bad at all & would certainly get better the more time they spent on the pitch. They are doing a lot of stuff right but obviously because they have some similarities, it will need a bit more work than two players who do it naturally.
Most people just expect stuff to work overnight these days, but that's not how football is. Some strike partnerships happen over time & have teething problems.
Aguero is our number one striker & he operates better with Negredo, but the 2nd pairing is not bad at all.
Have a look at how the rest of the team linked up together at Blackburn & find anything better.