It's been a decade since a La Masia player was promoted & fully integrated into the 1st team (S.Roberto) - a few have been promoted (Munir, Sandro etc.) and ultimately many have been used as commodities (Thiago, Rafinha, Adama, Deulofeu, Cucurella, Perez) rather than integrated fully. Some failed to succeed either due to injuries (Cuenca & Samper), lack of sufficient quality (Fontas, Bartra, Miranda, Tello, Montoya, Dos Santos, Lee Seung Woo) or simply poor development or integration (Olmo, Grimaldo, Dongou). Several were released as result of the FIFA ban (Kubo, Onana, Paik, Adekanye, Theo Chendri, Kais)
Overall - I would say the biggest talents that should've been integrating into the 1st team since 2010 should've been: Olmo, Grimaldo, Thiago, Kubo, Cucu, Onana, Chendri
The fact is only Ansu is being promoted at the moment with Puig also likely. Collado could be but predicated on what happens in the transfer market and whether another Catalan cantera product is counted on in Alena. Monchu is a gem who will likely come to the Premiership if he is not given a shot in the 1st team
Moriba, Konrad and Busquets are B team players with a big future likely ahead of them as well