Get yourself a 1970s A-Z and you'll see just how many roads have already been pedestrianised and made one-way. Cannon Street, Market Street, Albert Square past the front of the town hall heading south, busses only on Oxford Road and bits of Portland Street. Pedestrianisation and one-way systems aren't the answer they are part of the problem.
It might improve for a few months if they ever finish the M60 work, but will then be back to chaos when they turn the eastern side into a "not very smart" motorway.
And we need a proper ring road, not the wibbly, wobbly worm with more choke points than the Boston Strangler that we currently enjoy.
Every time a road is closed or has reduced width due to construction work we have even more problems as the alternatives have already been closed.