Just thinking about how the effect on the PL might pan out. Seem to be two possible scenarios at the moment- either the six get kicked out of the PL or they stay. If the former then presumably they get replaced from the Championship which on current standings would be Brentford, Bournemouth, Barnsley, Reading, Cardiff andMillwall. No disrespect to those clubs, but this would devalue the PL to the level of say the Belgian or Dutch leagues. For the PL the commercial implications of this scarcely bear thinking about so I don't see it happening.
If the six continue in the PL then as another poster has said they will mainly play their squad players as there is no incentive (eg top four and CL entry)for them to do otherwise, and plenty of disincentive (injury to star players). You might see the odd star player getting a run-out after injury for game time but that would be about it. And as the six will have more dosh than the others put together then we can expect to see their dominance in attracting the best squad players and positions in the PL.
Either way, the future for the PL does not look bright.
Incidentally , on the international front, if players from the six are banned these competitions are similarly devalued so I can't see that happening either, even if it's legal to ban them. Also banning them immediately drags players from countries outside Europe into this morasse.
What a bloody mess.